Small extracellular vesicles derived from umbilical cord mesenchymal stem cells repair blood-spinal cord barrier disruption after spinal cord injury through down-regulation of Endothelin-1 in rats.

Xue, Chenhui; Ma, Xun; Guan, Xiaoming; Feng, Haoyu; Zheng, Mingkui; Yang, Xihua

Xue, Chenhui; Ma, Xun; Guan, Xiaoming; Feng, Haoyu; Zheng, Mingkui; Yang, Xihua.

Afiliación

Xue C; Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Ma X; Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Guan X; Department of Orthopedics, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Feng H; Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Zheng M; Department of Orthopedics, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Yang X; Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.

PeerJ ; 11: e16311, 2023.

Article en En | MEDLINE | ID: mdl-37927780

Asunto(s)

Vesículas Extracelulares; Células Madre Mesenquimatosas; Traumatismos de la Médula Espinal; Ratas; Humanos; Animales; Regulación hacia Abajo; Endotelina-1/genética; Células Endoteliales/metabolismo; Ratas Sprague-Dawley; Traumatismos de la Médula Espinal/terapia; Células Madre Mesenquimatosas/metabolismo; Vesículas Extracelulares/metabolismo; Cordón Umbilical/metabolismo

Palabras clave

Blood-spinal cord barrier; Endothelin-1; Exosomes; Spinal cord injury; Stem cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos de la Médula Espinal / Células Madre Mesenquimatosas / Vesículas Extracelulares Límite: Animals / Humans Idioma: En Revista: PeerJ Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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