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[Early predictor of bronchial suture failure after pneumonectomy]. / Rannii prediktor nesostoyatel'nosti bronkhial'nogo shva posle pnevmonektomii.
Porkhanov, V A; Zhikharev, V A; Bushuev, A S; Zima, V S; Koryachkin, V A; Ivanova, M P.
Afiliación
  • Porkhanov VA; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia.
  • Zhikharev VA; Kuban State Medical University, Krasnodar, Russia.
  • Bushuev AS; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia.
  • Zima VS; Kuban State Medical University, Krasnodar, Russia.
  • Koryachkin VA; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia.
  • Ivanova MP; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia.
Khirurgiia (Mosk) ; (10): 71-77, 2023.
Article en Ru | MEDLINE | ID: mdl-37916560
OBJECTIVE: To identify the relationship between serum CRP/albumin and bronchial suture failure after pneumonectomy. MATERIAL AND METHODS: A retrospective analysis included 100 patients who underwent pneumonectomy with extended lymph node dissection for lung cancer. Patients were divided into 2 groups depending on postoperative complications: group 1 - bronchial stump failure, group 2 - no similar complications. In all patients, we analyzed markers of inflammation (C-reactive protein and albumin) in preoperative period and after 24 postoperative hours. Bronchial stump failure was found in 20 patients (10 patients (14.7%) after left-sided pneumonectomy and 10 (31%) patients after right-sided pneumonectomy). We found a significant relationship between serum CRP/albumin and bronchial stump failure after pneumonectomy (p<0.05). A prognostic formula was based on the ratio of serum C-reactive protein and albumin: PC = CRP/Alb, where PC - prognostic coefficient, CRP - serum C-reactive protein (mg/l) 24 hours after surgery, Alb - serum albumin (g/l) 24 hours after surgery. PC >2.6 determines high risk of bronchial stump failure after pneumonectomy, PC <2.6 - low risk. Sensitivity of this method is 90%, specificity - 97.5%.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fístula Bronquial / Neoplasias Pulmonares Límite: Humans Idioma: Ru Revista: Khirurgiia (Mosk) Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fístula Bronquial / Neoplasias Pulmonares Límite: Humans Idioma: Ru Revista: Khirurgiia (Mosk) Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia