The Fate of Angiotensin II in Placental Tissue and Blood.

Mizutani, Shigehiko; Mizutani, Hidesuke; Mizutani, Eita; Arita, Harumasa; Kajiyama, Hiroaki

Mizutani, Shigehiko; Mizutani, Hidesuke; Mizutani, Eita; Arita, Harumasa; Kajiyama, Hiroaki.

Afiliación

Mizutani S; Daiyabilding Lady's Clinic, Nagoya, Japan.
Mizutani H; Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine Faculty of Medicine, Nagoya, Japan.
Mizutani E; Daiyabilding Lady's Clinic, Nagoya, Japan.
Arita H; IP & License Strategy Division, Rohto Pharmaceutical Co.,Ltd., Osaka, Japan.
Kajiyama H; Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine Faculty of Medicine, Nagoya, Japan.

Horm Metab Res ; 2023 Dec 11.

Article en En | MEDLINE | ID: mdl-37913823

RESUMEN

The existence of a non-canonical pathway of renin-angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum, respectively.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Horm Metab Res Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania

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