Improving Intracellular Delivery of an Antibody-Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses In Vivo.

Nessler, Ian; Rubahamya, Baron; Kopp, Anna; Hofsess, Scott; Cardillo, Thomas M; Sathyanarayan, Nalini; Donnell, Jennifer; Govindan, Serengulam V; Thurber, Greg M

Nessler, Ian; Rubahamya, Baron; Kopp, Anna; Hofsess, Scott; Cardillo, Thomas M; Sathyanarayan, Nalini; Donnell, Jennifer; Govindan, Serengulam V; Thurber, Greg M.

Afiliación

Nessler I; Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan.
Rubahamya B; Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan.
Kopp A; Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan.
Hofsess S; Gilead Sciences, Inc., Morris Plains, New Jersey.
Cardillo TM; Gilead Sciences, Inc., Morris Plains, New Jersey.
Sathyanarayan N; Gilead Sciences, Inc., Morris Plains, New Jersey.
Donnell J; Gilead Sciences, Inc., Morris Plains, New Jersey.
Govindan SV; Gilead Sciences, Inc., Morris Plains, New Jersey.
Thurber GM; Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan.

Mol Cancer Ther ; 23(3): 343-353, 2024 Mar 04.

Article en En | MEDLINE | ID: mdl-37913500

Asunto(s)

Antineoplásicos; Inmunoconjugados; Animales; Antígeno Carcinoembrionario; Irinotecán; Línea Celular Tumoral; Anticuerpos Monoclonales

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Antineoplásicos Límite: Animals Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google