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Chemical composition and biological activities of essential oil from Grewia bulot leaves.
Pham, Ty Viet; Ho, Duc Viet; Tuan Le, Anh; Duy Ngo, Y; Thanh Thi Dang, Nhan; Quoc Le, Thang; Nguyen, Bao Chi.
Afiliación
  • Pham TV; Faculty of Chemistry, University of Education, Hue University, Hue City, Vietnam.
  • Ho DV; Faculty of Pharmacy, University of Medicine and Pharmacy, Hue University, Hue City, Vietnam.
  • Tuan Le A; Mien Trung Institute for Scientific Research, Vietnam National Museum of Nature, VAST, Hue City, Vietnam.
  • Duy Ngo Y; Faculty of Chemistry, University of Education, Hue University, Hue City, Vietnam.
  • Thanh Thi Dang N; Faculty of Chemistry, University of Education, Hue University, Hue City, Vietnam.
  • Quoc Le T; Faculty of Chemistry, University of Education, Hue University, Hue City, Vietnam.
  • Nguyen BC; Department of Science, Technology and International Relations, Hue University, Hue City, Vietnam.
Nat Prod Res ; : 1-7, 2023 Nov 01.
Article en En | MEDLINE | ID: mdl-37910669
This study focused on the chemical composition and biological activities of the essential oil derived from Grewia bulot, a plant species known for its medicinal properties. The analysis of Grewia bulot essential oil revealed the presence of 78 constituents. The major compounds were α-cadinol (13.5%), 1,8-cineole (12.7%), 1,10-di-epi-cubenol (9.8%), epi-α-cadinol (6.7%), (E,E)-α-farnesene (5.9%), (E)-citral (4.0%), selin-11-en-4-α-ol (4.0%), citronellol isobutanoate (3.9%), and geranic acid (3.7%). The essential oil exhibited promising antioxidant potential with an IC50 value of 452.65 ± 28.40 µg/mL in DPPH model. This oil did not show NO production inhibitory effect in RAW 264.7 cells. In addition, the essential oil exhibited significant cytotoxicity against KB, Hep-G2, MCF-7, and SK-LU-1 cancer cell lines, with IC50 values ranging from 44.04 ± 1.47 to 74.20 ± 3.71 µg/mL.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido