Sodium Citrate Nanoparticles Induce Dual-Path Pyroptosis for Enhanced Antitumor Immunotherapy through Synergistic Ion Overload and Metabolic Disturbance.

Li, Jing; Ding, Binbin; Tan, Jia; Chen, Hao; Meng, Qi; Li, Xinyang; Zheng, Pan; Ma, Ping'an; Lin, Jun

Li, Jing; Ding, Binbin; Tan, Jia; Chen, Hao; Meng, Qi; Li, Xinyang; Zheng, Pan; Ma, Ping'an; Lin, Jun.

Afiliación

Li J; State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Ding B; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China.
Tan J; State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Chen H; State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Meng Q; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China.
Li X; State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Zheng P; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China.
Ma P; State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Lin J; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China.

Nano Lett ; 23(21): 10034-10043, 2023 11 08.

Article en En | MEDLINE | ID: mdl-37903236

Asunto(s)

Nanopartículas; Neoplasias; Humanos; Piroptosis; Citrato de Sodio; Gasderminas; Péptidos y Proteínas de Señalización Intracelular; Neoplasias/tratamiento farmacológico; Inmunoterapia; Nanopartículas/uso terapéutico; Iones; Biomarcadores de Tumor; Proteínas Citotóxicas Formadoras de Poros

Palabras clave

immunotherapy; ion overload; metabolic regulation; pyroptosis; sodium citrate nanoparticle

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanopartículas / Neoplasias Límite: Humans Idioma: En Revista: Nano Lett Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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