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Cell-Tissue Interaction: The Biomimetic Approach to Design Tissue Engineered Biomaterials.
Nitti, Paola; Narayanan, Athira; Pellegrino, Rebecca; Villani, Stefania; Madaghiele, Marta; Demitri, Christian.
Afiliación
  • Nitti P; Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
  • Narayanan A; Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
  • Pellegrino R; Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
  • Villani S; Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
  • Madaghiele M; Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
  • Demitri C; Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
Bioengineering (Basel) ; 10(10)2023 Sep 25.
Article en En | MEDLINE | ID: mdl-37892852
The advancement achieved in Tissue Engineering is based on a careful and in-depth study of cell-tissue interactions. The choice of a specific biomaterial in Tissue Engineering is fundamental, as it represents an interface for adherent cells in the creation of a microenvironment suitable for cell growth and differentiation. The knowledge of the biochemical and biophysical properties of the extracellular matrix is a useful tool for the optimization of polymeric scaffolds. This review aims to analyse the chemical, physical, and biological parameters on which are possible to act in Tissue Engineering for the optimization of polymeric scaffolds and the most recent progress presented in this field, including the novelty in the modification of the scaffolds' bulk and surface from a chemical and physical point of view to improve cell-biomaterial interaction. Moreover, we underline how understanding the impact of scaffolds on cell fate is of paramount importance for the successful advancement of Tissue Engineering. Finally, we conclude by reporting the future perspectives in this field in continuous development.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bioengineering (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bioengineering (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza