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Unraveling the Multifaceted Role of the Golgi Apparatus: Insights into Neuronal Plasticity, Development, Neurogenesis, Alzheimer's Disease, and SARS-CoV-2 Interactions.
Toader, Corneliu; Eva, Lucian; Covache-Busuioc, Razvan-Adrian; Costin, Horia Petre; Glavan, Luca-Andrei; Corlatescu, Antonio Daniel; Ciurea, Alexandru Vlad.
Afiliación
  • Toader C; Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  • Eva L; Department of Vascular Neurosurgery, National Institute of Neurology and Neurovascular Diseases, 077160 Bucharest, Romania.
  • Covache-Busuioc RA; Faculty of Medicine, "Dunarea de Jos" University of Galati, 800201 Galați, Romania.
  • Costin HP; Emergency Clinical Hospital "Prof. dr. N. Oblu", 700309 Iasi, Romania.
  • Glavan LA; Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  • Corlatescu AD; Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  • Ciurea AV; Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Brain Sci ; 13(10)2023 Sep 23.
Article en En | MEDLINE | ID: mdl-37891732
This article critically evaluates the multifunctional role of the Golgi apparatus within neurological paradigms. We succinctly highlight its influence on neuronal plasticity, development, and the vital trafficking and sorting mechanisms for proteins and lipids. The discourse further navigates to its regulatory prominence in neurogenesis and its implications in Alzheimer's Disease pathogenesis. The emerging nexus between the Golgi apparatus and SARS-CoV-2 underscores its potential in viral replication processes. This consolidation accentuates the Golgi apparatus's centrality in neurobiology and its intersections with both neurodegenerative and viral pathologies. In essence, understanding the Golgi's multifaceted functions harbors profound implications for future therapeutic innovations in neurological and viral afflictions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Brain Sci Año: 2023 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Brain Sci Año: 2023 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza