Profound DNA methylomic differences between single- and multi-fraction alpha irradiations of lung fibroblasts.

Vera-Chang, Marilyn N; Danforth, John M; Stuart, Marilyne; Goodarzi, Aaron A; Brand, Marjorie; Richardson, Richard B

Vera-Chang, Marilyn N; Danforth, John M; Stuart, Marilyne; Goodarzi, Aaron A; Brand, Marjorie; Richardson, Richard B.

Afiliación

Vera-Chang MN; Radiobiology and Health Branch, Chalk River Laboratories, Canadian Nuclear Laboratories, Chalk River, ON, K0J 1J0, Canada.
Danforth JM; Departments of Biochemistry and Molecular Biology and Oncology, Cumming School of Medicine, Robson DNA Science Centre, Charbonneau Cancer Institute, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Stuart M; Environment and Waste Technologies Branch, Chalk River Laboratories, Canadian Nuclear Laboratories, Chalk River, ON, K0J 1J0, Canada.
Goodarzi AA; Departments of Biochemistry and Molecular Biology and Oncology, Cumming School of Medicine, Robson DNA Science Centre, Charbonneau Cancer Institute, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Brand M; Ottawa Hospital Research Institute, Ottawa, ON, K1H 8L6, Canada.
Richardson RB; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1H 8L6, Canada.

Clin Epigenetics ; 15(1): 174, 2023 10 27.

Article en En | MEDLINE | ID: mdl-37891670

Asunto(s)

Metilación de ADN; ADN; Humanos; Fibroblastos; Pulmón; Biomarcadores

Palabras clave

Aging; Alpha particles; Cancer; Lung; Methylome; Mitochondria; Radiation; Radon

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Metilación de ADN Límite: Humans Idioma: En Revista: Clin Epigenetics Año: 2023 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania

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