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Animal Metabolite Database: Metabolite Concentrations in Animal Tissues and Convenient Comparison of Quantitative Metabolomic Data.
Yanshole, Vadim V; Melnikov, Arsenty D; Yanshole, Lyudmila V; Zelentsova, Ekaterina A; Snytnikova, Olga A; Osik, Nataliya A; Fomenko, Maxim V; Savina, Ekaterina D; Kalinina, Anastasia V; Sharshov, Kirill A; Dubovitskiy, Nikita A; Kobtsev, Mikhail S; Zaikovskii, Anatolii A; Mariasina, Sofia S; Tsentalovich, Yuri P.
Afiliación
  • Yanshole VV; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Melnikov AD; Department of Physics, Novosibirsk State University, Pirogova Str. 1, Novosibirsk 630090, Russia.
  • Yanshole LV; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Zelentsova EA; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Snytnikova OA; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Osik NA; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Fomenko MV; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Savina ED; Department of Physics, Novosibirsk State University, Pirogova Str. 1, Novosibirsk 630090, Russia.
  • Kalinina AV; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Sharshov KA; Department of Physics, Novosibirsk State University, Pirogova Str. 1, Novosibirsk 630090, Russia.
  • Dubovitskiy NA; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Kobtsev MS; Laboratory of Proteomics and Metabolomics, International Tomography Center SB RAS, Institutskaya Str. 3a, Novosibirsk 630090, Russia.
  • Zaikovskii AA; Laboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Timakova Str. 2, Novosibirsk 630117, Russia.
  • Mariasina SS; Laboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Timakova Str. 2, Novosibirsk 630117, Russia.
  • Tsentalovich YP; Department of Information Technologies, Novosibirsk State University, Pirogova Str. 1, Novosibirsk 630090, Russia.
Metabolites ; 13(10)2023 Oct 17.
Article en En | MEDLINE | ID: mdl-37887413
The Animal Metabolite Database (AMDB, https://amdb.online) is a freely accessible database with built-in statistical analysis tools, allowing one to browse and compare quantitative metabolomics data and raw NMR and MS data, as well as sample metadata, with a focus on the metabolite concentrations rather than on the raw data itself. AMDB also functions as a platform for the metabolomics community, providing convenient deposition and exchange of quantitative metabolomic data. To date, the majority of the data in AMDB relate to the metabolite content of the eye lens and blood of vertebrates, primarily wild species from Siberia, Russia and laboratory rodents. However, data on other tissues (muscle, heart, liver, brain, and more) are also present, and the list of species and tissues is constantly growing. Typically, every sample in AMDB contains concentrations of 60-90 of the most abundant metabolites, provided in nanomoles per gram of wet tissue weight (nmol/g). We believe that AMDB will become a widely used tool in the community, as typical metabolite baseline concentrations in tissues of animal models will aid in a wide variety of fundamental and applied scientific fields, including, but not limited to, animal modeling of human diseases, assessment of medical formulations, and evolutionary and environmental studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Metabolites Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Metabolites Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Suiza