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Association of low diastolic blood pressure with cardiovascular outcomes and all-cause mortality: A meta-analysis.
Siddiqi, Tariq Jamal; Usman, Muhammad Shariq; Siddiqui, Amna; Salman, Ali; Talbot, Nicholas; Khan, Laibah Arshad; Shabbir, Aisha; Hall, Michael E; Taffet, George E.
Afiliación
  • Siddiqi TJ; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
  • Usman MS; Department of Medicine, University of Texas Southwestern, Dallas, TX, USA. Electronic address: shariqusman@outlook.com.
  • Siddiqui A; Department of Medicine, Karachi Medical and Dental College, Karachi, Pakistan.
  • Salman A; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
  • Talbot N; Department of Medicine, University of Texas Southwestern, Dallas, TX, USA.
  • Khan LA; Department of Medicine, King Edward Medical University, Lahore, Pakistan.
  • Shabbir A; Department of Medicine, King Edward Medical University, Lahore, Pakistan.
  • Hall ME; Associate Division Director, Division of Cardiovascular Diseases, Department of Medicine, University of Mississippi Medical Center.
  • Taffet GE; Professor of Medicine-Geriatrics, Department of Medicine, Baylor College of Medicine, Houston, TX, USA; Professor of Medicine, Department of Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Curr Probl Cardiol ; 49(1 Pt C): 102131, 2024 Jan.
Article en En | MEDLINE | ID: mdl-37866417
ABSTRACT

BACKGROUND:

Reduction of diastolic blood pressure (DBP) below 70 mmHg may decrease perfusion to the heart and worsen cardiovascular (CV) outcomes.

AIMS:

Explore the association between low DBP and CV outcomes.

METHODS:

We searched the online databases until August 2023 for studies reporting the risk of all-cause mortality (ACM) or CV outcomes in patients with low versus normal DBP (70-80mm Hg).

RESULTS:

Inclusion of 10 studies (n = 1,998,223 patients) found that a mean achieved DBP < 60 mmHg was associated with an increased risk of all-cause mortality (HR 1.48; 95 % CI [1.26-1.74]), especially in patients with pre-existing CV disease. It was also associated to a higher risk of major adverse cardiovascular events (HR 1.84; [1.28-2.65]) and myocardial infarction (HR 1.49; [1.13-1.97]). A DBP of 60-69 mmHg was associated with an increased risk of all-cause mortality (HR 1.11; [1.03-1.20]).

CONCLUSION:

Reduction of DBP, particularly below 60 mmHg, is associated with increased risk of ACM.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Accidente Cerebrovascular / Insuficiencia Cardíaca / Hipertensión / Infarto del Miocardio Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: Curr Probl Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Accidente Cerebrovascular / Insuficiencia Cardíaca / Hipertensión / Infarto del Miocardio Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: Curr Probl Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos