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Laser speckle contrast imaging, an alternative to laser doppler imaging in clinical practice of burn wound care derivation of a color code.
Dijkstra, Annemieke; Guven, Goksel; van Baar, Margriet E; Trommel, Nicole; Hofland, Helma W C; Kuijper, T Martijn; Ince, Can; Van der Vlies, C H.
Afiliación
  • Dijkstra A; van Weel Bethesda Hospital, Department of Intensive Care, Dirksland, the Netherlands. Electronic address: DijkstraA@maasstadziekenhuis.nl.
  • Guven G; Hacettepe University Faculty of Medicine, Department of Intensive Care, Ankara, Turkey.
  • van Baar ME; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands.
  • Trommel N; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands.
  • Hofland HWC; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands.
  • Kuijper TM; Maasstad Hospital, Department of Rheumatology, Rotterdam, the Netherlands.
  • Ince C; Erasmus Medical Center, Department of Translational Intensive Care, Rotterdam, the Netherlands.
  • Van der Vlies CH; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands. Electronic address: C.vandervlies@erasmusmc.nl.
Burns ; 49(8): 1907-1915, 2023 Dec.
Article en En | MEDLINE | ID: mdl-37863755
OBJECTIVE: To develop a color code and to investigate the validity of Laser Speckle Contrast Imaging (LSCI) for measuring burn wound healing potential (HP) in burn patients as compared to the reference standard Laser Doppler Imaging (LDI). METHOD: A prospective, observational, cohort study was conducted in adult patients with acute burn wounds. The relationship between mean flux measured with LDI and mean perfusion units (PU) measured with LSCI was expressed in a regression formula. Measurements were performed between 2 and 5 days after the burn wound. The creation of a LSCI color code was done by mapping the clinically validated color code of the LDI to the corresponding values on the LSCI scale. To assess validity of the LSCI, the ability of the LSCI to discriminate between HP < 14 and ≥ 14 days and HP < 21 and original ≥ 21 days according to the LDI reference standard was evaluated, with calculation of receiver operating characteristics (ROC) curves. RESULTS: A total of 50 patients were included with a median age of 40 years and total body surface area burned of 6%. LSCI values of 143 PU and 113 PU were derived as the cut-off values for the need of conservative treatment (HP < 14 and ≥ 14 days) resp. surgical closure (HP < 21 and ≥ 21 days). These LSCI cut off values showed a good discrimination between HP 14 days versus ≥ 14 days (Area Under Curve (AUC)= 0.89; sensitivity 85% and specificity = 82%) and a good discrimination between HP 21 days versus ≥ 21 days (AUC of 0.89, sensitivity 81% and specificity 88%). CONCLUSION: This is the first study in which a color code for the LSCI in adult clinical burn patients has been developed. Our study reconfirms the good performance of the LSCI for prediction of burn wound healing potential. This provides additional evidence for the potential value of the LSCI in specialized burn care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piel / Quemaduras Límite: Adult / Humans Idioma: En Revista: Burns Asunto de la revista: TRAUMATOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piel / Quemaduras Límite: Adult / Humans Idioma: En Revista: Burns Asunto de la revista: TRAUMATOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos