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Relationship between cognitive function affecting motor Functional Independence Measure and hypnotics.
Otsubo, Hiroko; Kishimoto, Keiko; Hirano, Iyori; Nakano, Hitoshi; Itaya, Kazuhiro; Kumaki, Ryota; Osumi, Hiroyuki.
Afiliación
  • Otsubo H; Division of Social Pharmacy and Pharmacy Department of Healthcare and Regulatory Sciences, School of Pharmacy, Showa University, Tokyo, Japan.
  • Kishimoto K; Department of Pharmacy, Ichigao Hospital, Yokohama, Japan.
  • Hirano I; Division of Social Pharmacy and Pharmacy Department of Healthcare and Regulatory Sciences, School of Pharmacy, Showa University, Tokyo, Japan.
  • Nakano H; Department of Rehabilitation, Ichigao Hospital, Yokohama, Japan.
  • Itaya K; Department of Rehabilitation, Ichigao Hospital, Yokohama, Japan.
  • Kumaki R; Department of Neurology, Ichigao Hospital, Yokohama, Japan.
  • Osumi H; Department of Neurology, Ichigao Hospital, Yokohama, Japan.
Jpn J Compr Rehabil Sci ; 13: 4-11, 2022.
Article en En | MEDLINE | ID: mdl-37859848
Otsubo H, Kishimoto K, Hirano I, Nakano H, Itaya K, Kumaki R, Osumi H. Relationship between cognitive function affecting motor Functional Independence Measure and hypnotics. Jpn J Compr Rehabil Sci 2022; 13: 4-11. Purpose: The purpose of this study was to examine the relationship between cognitive dysfunction affecting motor Functional Independence Measure (FIM) and hypnotics. Methods: This was a retrospective study involving 509 patients aged ≥ 65 years who were discharged from a convalescent rehabilitation ward. Results: Multiple regression analysis was performed with motor FIM efficiency and motor FIM effectiveness (motor FIM-e) as independent variables and the presence or absence of cognitive dysfunction as the dependent variable. The use of hypnotics in patients with cognitive dysfunction showed a positive relationship with motor FIM efficiency (ß = 0.147, P = 0.019) and motor FIM-e (ß = 0.141, P = 0.026). Multiple regression analyses were performed after further classifying hypnotics by therapeutic class into hypnotics with new mechanisms, non-benzodiazepine (BZ) hypnotics, and BZ hypnotics. Non-BZ hypnotics (ß = 0.141, P = 0.021) showed a positive relationship with motor FIM efficiency. Non-BZ hypnotics (ß = 0.158, P = 0.009) and BZ hypnotics (ß = 0.178, P = 0.003) showed a positive relationship with motor FIM-e, whereas hypnotics with new mechanisms of action did not. In contrast, none of the three combinations of hypnotics showed any significant relationship with either motor FIM efficiency or motor FIM-e in patients without cognitive dysfunction. Conclusion: The results suggested that the use of hypnotics in patients with cognitive dysfunction increases motor FIM efficiency and motor FIM-e.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Jpn J Compr Rehabil Sci Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Jpn J Compr Rehabil Sci Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón