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HummingFlow: novel single twist-drill access for ventricular drainage, irrigation, monitoring, and automated local drug delivery in subarachnoid hemorrhage.
Carrera, Diego A; Marsh, Laura M; Roach, Jessica J; Sarangarm, Preeyaporn; Cole, Chad D; Torbey, Michel T; Carlson, Andrew P.
Afiliación
  • Carrera DA; Departments of1Neurology and.
  • Marsh LM; 2Neurosurgery, University of New Mexico, Albuquerque; and.
  • Roach JJ; 3Neurosciences Intensive Care Unit and.
  • Sarangarm P; 4Department of Pharmacy, University of New Mexico Hospital, Albuquerque, New Mexico.
  • Cole CD; 2Neurosurgery, University of New Mexico, Albuquerque; and.
  • Torbey MT; Departments of1Neurology and.
  • Carlson AP; 2Neurosurgery, University of New Mexico, Albuquerque; and.
J Neurosurg ; 139(4): 1036-1041, 2023 10 01.
Article en En | MEDLINE | ID: mdl-37856891
OBJECTIVE: The management of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage (aSAH) remains one of the most important targets for neurocritical care. Advances in monitoring technology have facilitated a more thorough understanding of the pathophysiology and therapeutic approaches, but interventions are generally limited to either systemic therapies or passive CSF drainage. The authors present a novel approach that combines a multimodal monitoring bolt-based system with an irrigating ventricular drain capable of delivering intrathecal medications and describe their early experience in patients with aSAH. METHODS: The authors performed a retrospective review of cases treated with the combined Hummingbird multimodal bolt system and the IRRAflow irrigating ventriculostomy. RESULTS: Nine patients were treated with the combined multimodal bolt system with irrigating ventriculostomy approach. The median number of days to clearance of the third and fourth ventricles was 3 days in patients with obstructive intraventricular hemorrhage. Two patients received intrathecal alteplase for intraventricular hemorrhage clearance, and 2 patients received intrathecal nicardipine as rescue therapy for severe symptomatic angiographic vasospasm. CONCLUSIONS: Combined CSF drainage, irrigation, multimodality monitoring, and automated local drug delivery are feasible using a single twist-drill hole device. Further investigation of irrigation settings and treatment approaches in high-risk cases is warranted.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Subaracnoidea / Vasoespasmo Intracraneal Límite: Humans Idioma: En Revista: J Neurosurg Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Subaracnoidea / Vasoespasmo Intracraneal Límite: Humans Idioma: En Revista: J Neurosurg Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos