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Stereotactic radiosurgery for orbital cavernous hemangiomas.
Chen, You-Cong; Tsai, Chieh-Chih; Chen, Shih-Jen; Wu, Hsiu-Mei; Yang, Huai-Che; Chen, Ching-Jen; Hu, Yong-Sin; Lin, Chung-Jung; Guo, Wan-Yuo; Pan, David Hung-Chi; Chung, Wen-Yuh; Lee, Cheng-Chia.
Afiliación
  • Chen YC; 1Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
  • Tsai CC; 2School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Chen SJ; 2School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Wu HM; Departments of3Ophthalmology and.
  • Yang HC; 2School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Chen CJ; Departments of3Ophthalmology and.
  • Hu YS; 2School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Lin CJ; 4Radiology, Taipei Veterans General Hospital, Taipei, Taiwan.
  • Guo WY; 1Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
  • Pan DH; 2School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Chung WY; 6Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia; and.
  • Lee CC; 2School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
J Neurosurg ; 138(6): 1622-1629, 2023 06 01.
Article en En | MEDLINE | ID: mdl-37856889
OBJECTIVE: The goal of this study was to assess the safety and efficacy of single-session Gamma Knife radiosurgery (GKRS) for orbital cavernous hemangiomas (OCHs). METHODS: Patients who presented with an OCH between September 1999 and May 2022 and were treated with single-session GKRS were included in this single-center cohort study. RESULTS: There were 23 patients (7 males and 16 females) in this study. The median margin dose was 12 Gy (range 11-13 Gy). The median clinical and radiological follow-ups were 45 months (range 5-190 months) and 45 months (range 6-190 months), respectively. Nine (69.2%) of 13 patients with visual acuity impairment had improvement in best corrected visual acuity. Of the 8 patients with visual field defects, 5 patients (62.5%) had complete resolution. Tumor regression was observed in 22 patients (95.7%). The mean relative reduction in tumor volume was 82.6% ± 23.7%. The relative reductions in tumor volume were 33%, 49%, 72%, 84%, and 89% at 6, 12, 24, 36, and 48 months, respectively. Adverse effects of radiation were not observed. CONCLUSIONS: GKRS appears to be safe and efficacious for treating OCHs over long-term follow-up. The treatment is associated with a high rate of regression in OCHs and remarkable improvement in both visual acuity and visual field deficits.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radiocirugia / Hemangioma Cavernoso Límite: Female / Humans / Male Idioma: En Revista: J Neurosurg Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radiocirugia / Hemangioma Cavernoso Límite: Female / Humans / Male Idioma: En Revista: J Neurosurg Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos