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Fluorescence imaging of peripheral nerve function and structure.
Yang, Xiaoqi; Zhang, Yumin; Liu, Yadong; Wang, Yuanyi; Zhou, Nan.
Afiliación
  • Yang X; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou 450052, Henan, China. fcczhoun@zzu.edu.cn.
  • Zhang Y; Department of Geriatric Endocrinology, The First Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210029, P. R. China.
  • Liu Y; Department of Spinal Surgery, The First Hospital of Jilin University, Jilin Engineering Research Center For Spine and Spinal Cord Injury, 1 Xinmin St, Changchun, 130021, China. wangyuanyi@jlu.edu.cn.
  • Wang Y; Department of Spinal Surgery, The First Hospital of Jilin University, Jilin Engineering Research Center For Spine and Spinal Cord Injury, 1 Xinmin St, Changchun, 130021, China. wangyuanyi@jlu.edu.cn.
  • Zhou N; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou 450052, Henan, China. fcczhoun@zzu.edu.cn.
J Mater Chem B ; 11(42): 10052-10071, 2023 11 01.
Article en En | MEDLINE | ID: mdl-37846619
Peripheral nerve injuries are common and can cause catastrophic consequences. Although peripheral nerves have notable regenerative capacity, full functional recovery is often challenging due to a number of factors, including age, the type of injury, and delayed healing, resulting in chronic disorders that cause lifelong miseries and significant financial burdens. Fluorescence imaging, among the various techniques, may be the key to overcome these restrictions and improve the prognosis because of its feasibility and dynamic real-time imaging. Intraoperative dynamic fluorescence imaging allows the visualization of the morphological structure of the nerve so that surgeons can reduce the incidence of medically induced injury. Axoplasmic transport-based neuroimaging allows the visualization of the internal transport function of the nerve, facilitating early, objective, and accurate assessment of the degree of regenerative repair, allowing early intervention in patients with poor recovery, thereby improving prognosis. This review briefly discusses peripheral nerve fluorescent dyes that have been reported or could potentially be employed, with a focus on their role in visualizing the nerve's function and anatomy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nervios Periféricos / Traumatismos de los Nervios Periféricos Límite: Humans Idioma: En Revista: J Mater Chem B Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nervios Periféricos / Traumatismos de los Nervios Periféricos Límite: Humans Idioma: En Revista: J Mater Chem B Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido