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2,4-Diacetylphloroglucinol (DAPG) derivatives rapidly eradicate methicillin-resistant staphylococcus aureus without resistance development by disrupting membrane.
Zhong, Yifan; He, Xiaoli; Tao, Wenlan; Feng, Jizhou; Zhang, Ruixue; Gong, Hongzhi; Tang, Ziyi; Huang, Chao; He, Yun.
Afiliación
  • Zhong Y; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China.
  • He X; Chongqing School, University of Chinese Academy of Sciences (UCAS Chongqing), Chongqing, PR China; Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, PR China.
  • Tao W; Chongqing School, University of Chinese Academy of Sciences (UCAS Chongqing), Chongqing, PR China; Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, PR China.
  • Feng J; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China.
  • Zhang R; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China.
  • Gong H; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China.
  • Tang Z; Chongqing School, University of Chinese Academy of Sciences (UCAS Chongqing), Chongqing, PR China; Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, PR China.
  • Huang C; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China. Electronic address: chuang@cqu.edu.cn.
  • He Y; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China; Chongqing School, University of Chinese Academy of Sciences (UCAS Chongqing), Chongqing, PR China; BayRay Innovation Center, Shenzhen Bay Lab
Eur J Med Chem ; 261: 115823, 2023 Dec 05.
Article en En | MEDLINE | ID: mdl-37839345
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus Resistente a Meticilina Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus Resistente a Meticilina Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article Pais de publicación: Francia