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The OsCPK17-OsPUB12-OsRLCK176 module regulates immune homeostasis in rice.
Mou, Baohui; Zhao, Guosheng; Wang, Jiyang; Wang, Shanzhi; He, Feng; Ning, Yuese; Li, Dayong; Zheng, Xinhang; Cui, Fuhao; Xue, Fang; Zhang, Shiyong; Sun, Wenxian.
Afiliación
  • Mou B; Department of Plant Pathology, The Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, and Joint International Research Laboratory of Crop Molecular Breeding, Ministry of Education, China Agricultural University, Beijing 100193, China.
  • Zhao G; Department of Plant Pathology, The Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, and Joint International Research Laboratory of Crop Molecular Breeding, Ministry of Education, China Agricultural University, Beijing 100193, China.
  • Wang J; Department of Plant Pathology, The Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, and Joint International Research Laboratory of Crop Molecular Breeding, Ministry of Education, China Agricultural University, Beijing 100193, China.
  • Wang S; Department of Plant Pathology, The Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, and Joint International Research Laboratory of Crop Molecular Breeding, Ministry of Education, China Agricultural University, Beijing 100193, China.
  • He F; College of Plant Protection, Southwest University, Chongqing 400715, China.
  • Ning Y; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
  • Li D; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
  • Zheng X; College of Plant Protection, Jilin Agricultural University, Changchun, Jilin 130118, China.
  • Cui F; Department of Plant Pathology, The Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, and Joint International Research Laboratory of Crop Molecular Breeding, Ministry of Education, China Agricultural University, Beijing 100193, China.
  • Xue F; Department of Plant Pathology, The Ministry of Agriculture Key Laboratory of Pest Monitoring and Green Management, and Joint International Research Laboratory of Crop Molecular Breeding, Ministry of Education, China Agricultural University, Beijing 100193, China.
  • Zhang S; Wetland Agriculture and Ecology Institute, Shandong Academy of Agricultural Sciences, Jinan 250100, Shandong, China.
  • Sun W; Wetland Agriculture and Ecology Institute, Shandong Academy of Agricultural Sciences, Jinan 250100, Shandong, China.
Plant Cell ; 36(4): 987-1006, 2024 Mar 29.
Article en En | MEDLINE | ID: mdl-37831412
Plant immunity is fine-tuned to balance growth and defense. However, little is yet known about molecular mechanisms underlying immune homeostasis in rice (Oryza sativa). In this study, we reveal that a rice calcium-dependent protein kinase (CDPK), OsCPK17, interacts with and stabilizes the receptor-like cytoplasmic kinase (RLCK) OsRLCK176, a close homolog of Arabidopsis thaliana BOTRYTIS-INDUCED KINASE 1 (AtBIK1). Oxidative burst and pathogenesis-related gene expression triggered by pathogen-associated molecular patterns are significantly attenuated in the oscpk17 mutant. The oscpk17 mutant and OsCPK17-silenced lines are more susceptible to bacterial diseases than the wild-type plants, indicating that OsCPK17 positively regulates rice immunity. Furthermore, the plant U-box (PUB) protein OsPUB12 ubiquitinates and degrades OsRLCK176. OsCPK17 phosphorylates OsRLCK176 at Ser83, which prevents the ubiquitination of OsRLCK176 by OsPUB12 and thereby enhances the stability and immune function of OsRLCK176. The phenotypes of the ospub12 mutant in defense responses and disease resistance show that OsPUB12 negatively regulates rice immunity. Therefore, OsCPK17 and OsPUB12 reciprocally maintain OsRLCK176 homeostasis and function as positive and negative immune regulators, respectively. This study uncovers positive cross talk between CDPK- and RLCK-mediated immune signaling in plants and reveals that OsCPK17, OsPUB12, and OsRLCK176 maintain rice immune homeostasis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oryza Idioma: En Revista: Plant Cell Asunto de la revista: BOTANICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oryza Idioma: En Revista: Plant Cell Asunto de la revista: BOTANICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido