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Activation of human STING by a molecular glue-like compound.
Li, Jie; Canham, Stephen M; Wu, Hua; Henault, Martin; Chen, Lihao; Liu, Guoxun; Chen, Yu; Yu, Gary; Miller, Howard R; Hornak, Viktor; Brittain, Scott M; Michaud, Gregory A; Tutter, Antonin; Broom, Wendy; Digan, Mary Ellen; McWhirter, Sarah M; Sivick, Kelsey E; Pham, Helen T; Chen, Christine H; Tria, George S; McKenna, Jeffery M; Schirle, Markus; Mao, Xiaohong; Nicholson, Thomas B; Wang, Yuan; Jenkins, Jeremy L; Jain, Rishi K; Tallarico, John A; Patel, Sejal J; Zheng, Lianxing; Ross, Nathan T; Cho, Charles Y; Zhang, Xuewu; Bai, Xiao-Chen; Feng, Yan.
Afiliación
  • Li J; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Canham SM; Novartis Institutes for BioMedical Research, Cambridge, MA, USA. steve.canham@novartis.com.
  • Wu H; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Henault M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Chen L; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Liu G; Novartis Institutes for BioMedical Research, San Diego, CA, USA.
  • Chen Y; Novartis Institutes for BioMedical Research, San Diego, CA, USA.
  • Yu G; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Miller HR; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Hornak V; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Brittain SM; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Michaud GA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Tutter A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Broom W; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Digan ME; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • McWhirter SM; Aduro Biotech, Inc., Berkeley, CA, USA.
  • Sivick KE; Aduro Biotech, Inc., Berkeley, CA, USA.
  • Pham HT; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Chen CH; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Tria GS; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • McKenna JM; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Schirle M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Mao X; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Nicholson TB; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Wang Y; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Jenkins JL; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Jain RK; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Tallarico JA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Patel SJ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Zheng L; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Ross NT; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Cho CY; Novartis Institutes for BioMedical Research, San Diego, CA, USA.
  • Zhang X; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA. xuewu.zhang@utsouthwestern.edu.
  • Bai XC; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA. xuewu.zhang@utsouthwestern.edu.
  • Feng Y; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA. xiaochen.bai@utsouthwestern.edu.
Nat Chem Biol ; 20(3): 365-372, 2024 Mar.
Article en En | MEDLINE | ID: mdl-37828400
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Adaptadoras Transductoras de Señales / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Adaptadoras Transductoras de Señales / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos