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Pembrolizumab-Associated Pneumonitis Resembling Lymphangitic Carcinomatosis in a Melanoma Patient.
Umehana, Masaki; Hosono, Makoto; Hijikata, Yoichiro; Takahashi, Mina; Kanagaki, Mitsunori.
Afiliación
  • Umehana M; From the Department of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo.
  • Hosono M; Department of Radiology, Kindai University Faculty of Medicine, Osaka.
  • Hijikata Y; From the Department of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo.
  • Takahashi M; Department of Plastic and Reconstructive Surgery, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.
  • Kanagaki M; From the Department of Diagnostic Radiology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo.
Clin Nucl Med ; 48(11): e529-e531, 2023 Nov 01.
Article en En | MEDLINE | ID: mdl-37793162
ABSTRACT: In recent years, many articles have described the adverse events associated with immune checkpoint inhibitors. We report the case of a 63-year-old woman with bilateral lung shadows after 1-year pembrolizumab immunotherapy following surgery for the right-foot melanoma because of positive sentinel lymph nodes. Follow-up 18 F-FDG PET/CT demonstrated bilateral diffuse mass-like peribronchovascular opacities with marked FDG uptake. Clinically, melanoma metastases with lymphangitic spread were suspected, and bronchoscopy was performed, although no evidence of malignancy was found. The lung shadow was mostly resolved after steroid treatment. Pembrolizumab-induced pneumonitis can be a mimicker of melanoma metastasis with lymphangitic spread.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía / Carcinoma / Neoplasias Pulmonares / Melanoma Tipo de estudio: Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Clin Nucl Med Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía / Carcinoma / Neoplasias Pulmonares / Melanoma Tipo de estudio: Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Clin Nucl Med Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos