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Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.
Tsioras, Konstantinos; Smith, Kevin C; Edassery, Seby L; Garjani, Mehraveh; Li, Yichen; Williams, Chloe; McKenna, Elizabeth D; Guo, Wenxuan; Wilen, Anika P; Hark, Timothy J; Marklund, Stefan L; Ostrow, Lyle W; Gilthorpe, Jonathan D; Ichida, Justin K; Kalb, Robert G; Savas, Jeffrey N; Kiskinis, Evangelos.
Afiliación
  • Tsioras K; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Smith KC; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Edassery SL; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Garjani M; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Li Y; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Zilkha Neurogenetic Institute, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA.
  • Williams C; Department of Integrative Medical Biology, Umeå University, 90187 Umeå, Sweden.
  • McKenna ED; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Guo W; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Zilkha Neurogenetic Institute, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA.
  • Wilen AP; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Hark TJ; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Marklund SL; Department of Medical Biosciences, Clinical Chemistry, Umeå University, 90187 Umeå, Sweden.
  • Ostrow LW; Department of Neurology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
  • Gilthorpe JD; Department of Integrative Medical Biology, Umeå University, 90187 Umeå, Sweden.
  • Ichida JK; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Zilkha Neurogenetic Institute, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA.
  • Kalb RG; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Savas JN; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Kiskinis E; The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL 6061
Cell Rep ; 42(10): 113160, 2023 10 31.
Article en En | MEDLINE | ID: mdl-37776851
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos