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Sex-related differences in non-ischemic myocardial injury in the emergency department: A real-world perspective.
Golino, Michele; Morello, Matteo; Marazzato, Jacopo; Blasi, Federico; Chierchia, Valentina; Oliva, Carlo-Agostino; Zappa, Martina; Ageno, Walter; Passi, Alberto; Angeli, Fabio; De Ponti, Roberto.
Afiliación
  • Golino M; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy. Electronic address: mgolino@uninsubria.it.
  • Morello M; Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy; School of Cardiology, University of Brescia, 25121 Brescia, Italy.
  • Marazzato J; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
  • Blasi F; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
  • Chierchia V; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
  • Oliva CA; Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy; School of Cardiology, University of Brescia, 25121 Brescia, Italy.
  • Zappa M; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy; Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institute, IRCCS Tradate, 21049 Tradate, Italy.
  • Ageno W; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy; Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.
  • Passi A; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy; Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.
  • Angeli F; Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institute, IRCCS Tradate, 21049 Tradate, Italy; Department of Medicine and Technological Innovation (DiMIT), University of Insubria, 21100 Varese, Italy.
  • De Ponti R; Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy; Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.
Int J Cardiol ; 395: 131394, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-37748523
ABSTRACT

BACKGROUND:

Myocardial injury is associated with adverse outcomes. No data are reported about sex differences in incidence and factors associated with myocardial injury in an emergency department (ED) setting from a real-world perspective. We aimed to assess whether sex plays a major role in the diagnosis of myocardial injury in the ED.

METHODS:

In this subanalysis of a retrospective study, patients presenting at the ED with at least one high-sensitivity cardiac troponin T (hs-cTnT) value and without acute coronary syndromes diagnosis were compared.

RESULTS:

31,383 patients were admitted to the ED, 4660 had one hs-cTnT value, and 3937 were enrolled 1943 females (49.4%) and 1994 males (50.6%). The diagnosis of myocardial injury was higher among men (36.8% vs. 32.9%, p < 0.01). Male sex was independently associated with myocardial injury. An older age, an elevated NT-proB-type Natriuretic Peptide and a lower estimated glomerular filtrate rate were independently associated with myocardial injury in both sexes.

CONCLUSIONS:

In the ED, from a real-world perspective, myocardial injury occurred more frequently in males, and it was associated with older age and the presence of cardiac, lung, and kidney disease but not higher hs-cTnT values.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome Coronario Agudo / Lesiones Cardíacas Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome Coronario Agudo / Lesiones Cardíacas Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos