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Ligulariatinside A, a new sesquiterpene glycoside from roots of Ligularia veitchiana.
Bai, Jie; Wang, Si-Yao; Pan, Kang; Luo, Hua-Jun; Zou, Kun; Wang, Hui.
Afiliación
  • Bai J; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.
  • Wang SY; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.
  • Pan K; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.
  • Luo HJ; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.
  • Zou K; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.
  • Wang H; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.
Nat Prod Res ; : 1-7, 2023 Sep 25.
Article en En | MEDLINE | ID: mdl-37746700
A new sesquiterpene glycoside, ligulariatinside A (1), along with nine known compounds, dibutyl phthalate (2), 1-O-(9Z,12Z-octadecadienoyl) glycerol (3), bis (2-ethylhexyl) phthalate (4), 4-hydroxy-3-methoxyphenylpropanol (5), dihydrosyringenin (6), caffeic acid (7), 6ß-hydroxy-7(11)-eremophilen-12,8α-olide (8), together with the mixture of 6ß,8ß-dihydroxyeremophil-7(11)-en-12,8α-olide (9) and 6ß,8α-dihydroxy-eremophil-7(11)-en-12,8ß-olide (10) were isolated from roots of L. veitchiana. Structures of these compounds were elucidated by comprehensive analyses of HRESIMS, 1D NMR, and 2D NMR spectroscopic data. Compounds 2 and 4 are not likely natural compounds but contaminants. All isolated compounds were tested for antibacterial activity. Compounds 1, 5, 6, together with the mixture of 9 and 10, showed mild activity against Vibrio anguillarum, with MIC values of 50, 50, 100, and 200 µg/mL, while compound 7 showed moderate activity against Vibrio anguillarum, with a MIC value of 25 µg/mL.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido