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Herpes simplex Virus Pneumonitis in an Acute/Subacute Paracoccidioidomycosis Patient With Malabsorption Syndrome. Case-Report and Literature Review.
Cavalcante, Ricardo S; Souza, Bruno S; Duarte, Iverson X; Moraes, Marcelo P T; Coelho, Kunie I R; Griva, Beatriz L; Pereira, Beatriz A S; Calvi, Sueli A; Betini, Marluci; Mendes, Rinaldo P.
Afiliación
  • Cavalcante RS; Tropical Diseases Area, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Souza BS; Tropical Diseases Area, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Duarte IX; Department of Pathology, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Moraes MPT; Department of Pathology, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Coelho KIR; Department of Pathology, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Griva BL; Nuclear Medicine Service, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Pereira BAS; Tropical Diseases Area, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Calvi SA; Tropical Diseases Area, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
  • Betini M; University Library, São Paulo State University-UNESP, Botucatu, Brazil.
  • Mendes RP; Tropical Diseases Area, School of Medicine, São Paulo State University-UNESP, Botucatu, Brazil.
Front Fungal Biol ; 2: 805502, 2021.
Article en En | MEDLINE | ID: mdl-37744114
Paracoccidioides sp.-Herpes simplex virus (HSV) co-infection was not reported until now and malabsorption syndrome is a rare complication of the acute/subacute form (AF) of paracoccidioidomycosis (PCM), characterized by life-threatening abnormalities, such as fat and protein loss, lymphopenia, ascites, and intense immunosuppression. A 21-year-old woman presented the PCM AF with intense involvement of the abdominal and intestinal lymphoid organs, which leads to the malabsorption syndrome and severe immunosuppression. This patient developed a fatal-disseminated HSV infection associated with the paracoccidioidal disease. This case demonstrates that, in addition to the antigen-specific immunosuppression, some PCM patients can present a generalized cell-mediated immune depression and endogenous infection of latent microorganisms. On the best of our knowledge, this is the first report of an association between PCM and HSV infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Fungal Biol Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Fungal Biol Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza