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Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML.
Man, Cheuk-Him; Lam, Wing; Dang, Chee-Chean; Zeng, Xiao-Yuan; Zheng, Li-Chuan; Chan, Natalie Nok-Man; Ng, Ka-Lam; Chan, Koon-Chuen; Kwok, Tsz-Ho; Ng, Timothy Chi-Chun; Leung, Wing-Yan; Huen, Michael Shing-Yan; Wong, Carmen Chak-Lui; So, Chi Wai Eric; Dou, Zhixun; Goyama, Susumu; Bray, Mark Robert; Mak, Tak Wah; Leung, Anskar Yu-Hung.
Afiliación
  • Man CH; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Lam W; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Dang CC; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Zeng XY; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Zheng LC; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Chan NN; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Ng KL; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Chan KC; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Kwok TH; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Ng TC; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Leung WY; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Huen MS; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Wong CC; Department of Pathology, The University of Hong Kong, Hong Kong SAR, China.
  • So CWE; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong SAR, China.
  • Dou Z; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China.
  • Goyama S; Department of Haematological Medicine, Leukemia and Stem Cell Biology Team, King's College London, London, UK.
  • Bray MR; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
  • Mak TW; Harvard Stem Cell Institute, Harvard University, Cambridge, MA.
  • Leung AY; Division of Molecular Oncology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
Blood ; 142(23): 2002-2015, 2023 12 07.
Article en En | MEDLINE | ID: mdl-37738460

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histonas / Leucemia Mieloide Aguda Límite: Animals Idioma: En Revista: Blood Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histonas / Leucemia Mieloide Aguda Límite: Animals Idioma: En Revista: Blood Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos