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Association between new plasma inflammatory markers and risk of colorectal neoplasms in individuals over 50 years old.
Su, Jia-Yi; Wang, Yun; Wu, Shang-Shang; Li, Wen-Kun; Wang, Cheng-Yao; Ma, Jiu-Yue; Qiu, Yu-Ting; Zhou, Min-Si; Wang, Zhan; Li, Peng; Liu, Chun-Tao; Wu, Jing.
Afiliación
  • Su JY; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
  • Wang Y; National Clinical Research Center for Digestive Diseases, Beijing 100050, China.
  • Wu SS; Beijing Digestive Disease Center, Beijing 100050, China.
  • Li WK; Department of Presbyatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
  • Wang CY; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
  • Ma JY; National Clinical Research Center for Digestive Diseases, Beijing 100050, China.
  • Qiu YT; Beijing Digestive Disease Center, Beijing 100050, China.
  • Zhou MS; Department of Clinical Epidemiology and Evidence-based Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
  • Wang Z; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
  • Li P; National Clinical Research Center for Digestive Diseases, Beijing 100050, China.
  • Liu CT; Beijing Digestive Disease Center, Beijing 100050, China.
  • Wu J; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Carcinogenesis ; 44(12): 824-836, 2023 12 30.
Article en En | MEDLINE | ID: mdl-37713476
OBJECTIVE(S): The prognostic value of systemic cytokine profiles and inflammatory markers in colorectal cancer were explored by several studies. We want to know more about inflammatory biomarkers in colorectal adenoma and early cancer. METHOD: The level of 38 inflammatory markers in the plasma of 112 adenoma patients, 72 Tis-T1 staging of colorectal carcinoma patients, 34 T2-T4 staging of colorectal carcinoma patients and 53 normal subjects were detected and compared. RESULT(S): Eight inflammatory biomarkers (Eotaxin, GCSF, IL-4, IL-5, IL-17E, MCP-1, TNF-α and VEGF-A) have higher plasma concentrations in colorectal adenoma and cancer patients compared with normal participants over 50 years old. CONCLUSION(S): Inflammatory markers may have the prognostic value for colorectal adenoma and early-stage carcinoma.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Adenoma Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans / Middle aged Idioma: En Revista: Carcinogenesis Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Adenoma Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans / Middle aged Idioma: En Revista: Carcinogenesis Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido