Effects of external environment on promoter methylation of PIK3R5 and related pathway regulation in steroid-induced femoral head necrosis.

Qin, Wentao; Jiang, Mingyang; Lu, Shenyi; Hu, Yang; Gan, Fu; Fang, Weijun; Chen, Dongxu; Bo, Zhandong

Qin, Wentao; Jiang, Mingyang; Lu, Shenyi; Hu, Yang; Gan, Fu; Fang, Weijun; Chen, Dongxu; Bo, Zhandong.

Afiliación

Qin W; Department of Bone and Joint Surgery, Guangxi Medical University First Affiliated Hospital, Nanning, China.
Jiang M; Department of Bone and Joint Surgery, Guangxi Medical University First Affiliated Hospital, Nanning, China.
Lu S; Department of Rehabilitation, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Hu Y; Department of Bone and Joint Surgery, Guangxi Medical University First Affiliated Hospital, Nanning, China; Department of Sports Medicine and Joint Surgery, Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guilin, China.
Gan F; Department of Rehabilitation, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Fang W; Department of Emergency, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. Electronic address: fangwj@whu.edu.cn.
Chen D; Department of Sports Medicine and Joint Surgery, Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guilin, China. Electronic address: drchendongxu@126.com.
Bo Z; Department of Bone and Joint Surgery, Guangxi Medical University First Affiliated Hospital, Nanning, China. Electronic address: drrbozhandong@126.com.

Environ Res ; 238(Pt 1): 117116, 2023 12 01.

Article en En | MEDLINE | ID: mdl-37709244

Asunto(s)

Necrosis de la Cabeza Femoral; Humanos; Animales; Conejos; Necrosis de la Cabeza Femoral/inducido químicamente; Necrosis de la Cabeza Femoral/genética; Necrosis de la Cabeza Femoral/patología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Proteínas Proto-Oncogénicas c-akt/farmacología; Metilación; Cabeza Femoral/metabolismo; Cabeza Femoral/patología; Fosfatidilinositol 3-Quinasas/metabolismo; Fosfatidilinositol 3-Quinasas/farmacología; Esteroides/toxicidad; Esteroides/metabolismo; Hormonas/metabolismo

Palabras clave

Environmental factor; PIK3R5; SANFH; Steroid hormones

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Necrosis de la Cabeza Femoral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Environ Res Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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