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How to study subjective experience in an animal model of blindsight?
Yu, Xiyao; Yamaguchi, Reona; Isa, Tadashi.
Afiliación
  • Yu X; Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
  • Yamaguchi R; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501, Japan.
  • Isa T; Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501, Japan. Electronic address: isa.tadashi.7u@kyoto-u.ac.jp.
Neurosci Res ; 201: 39-45, 2024 Apr.
Article en En | MEDLINE | ID: mdl-37696449
The nature of subjective conscious experience, which accompanies us throughout our waking lives, and how it is generated, remain elusive. One of the challenges in studying subjective experience is disentangling the brain activity related to the sensory stimulus processing and stimulus-guided behavior from those associated with subjective perception. Blindsight, a phenomenon characterized by the retained visual discrimination performance but impaired visual consciousness due to damage to the primary visual cortex, becomes a special entry point to address this question. However, to fully understand the underlying neural mechanism, relying on studies involving human patients alone is insufficient. In this paper, we tried to address this issue, by first introducing the well-known cases of blindsight, especially the reports on subjective experience in both human and monkey subjects. And then we described how the impaired visual awareness of blindsight monkeys has been discovered and further studied by specifically designed tasks, as verbal reporting is not possible for these animals. Our previous studies also demonstrated that many complex visually guided cognitive processes were still retained despite the impairment of visual awareness. Further investigation needs to be conducted to explore the relationship between visually guided behavior, visual awareness and brain activity in blindsight subjects.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Visual Límite: Animals / Humans Idioma: En Revista: Neurosci Res Asunto de la revista: NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Visual Límite: Animals / Humans Idioma: En Revista: Neurosci Res Asunto de la revista: NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Irlanda