Your browser doesn't support javascript.
loading
The Activity of Adenosine Deaminase and Dipeptidyl Peptidase IV in Children With Attention Deficit Hyperactivity Disorder.
Naralan, Yüksel Sümeyra; Dogan, Özlem; Elgün, Serenay; Öztop, Didem Behice; Kiliç, Birim Günay.
Afiliación
  • Naralan YS; Rize Recep Tayyip Erdogan Training and Research Hospital, Turkey.
  • Dogan Ö; Ankara University School of Medicine, Turkey.
  • Elgün S; Ankara University School of Medicine, Turkey.
  • Öztop DB; Ankara University School of Medicine, Turkey.
  • Kiliç BG; Ankara University School of Medicine, Turkey.
J Atten Disord ; 28(1): 25-30, 2024 01.
Article en En | MEDLINE | ID: mdl-37695015
ABSTRACT

OBJECTIVE:

In this study, to investigate the place of T cell-mediated immunity in the etiology of ADHD, for which we do not have enough information; we aimed to investigate the activity of DPP IV and ADA, which are T cell-related enzymes, and the relationship of these enzymes with ADHD symptoms in children with ADHD.

METHODS:

Twenty-seven children aged 6 to 12 years with a diagnosis of attention deficit hyperactivity disorder and 27 children aged 6 to 12 years without any psychiatric disease were included in the study.

RESULTS:

While serum ADA and DPP-IV activity were found to be statistically significantly higher in the group with ADHD. There was no statistically significant correlation between serum ADA and DPP-IV activities and CTRS-R-L and CPRS-R-L in both groups.

CONCLUSION:

We think that T cell mediated inflammation may play a role in the etiology of ADHD due to changes in ADA and DPP-IV levels in children.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno por Déficit de Atención con Hiperactividad Límite: Child / Humans Idioma: En Revista: J Atten Disord Asunto de la revista: PSICOLOGIA / PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno por Déficit de Atención con Hiperactividad Límite: Child / Humans Idioma: En Revista: J Atten Disord Asunto de la revista: PSICOLOGIA / PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos