JNTX-101, a novel albumin-encapsulated gemcitabine prodrug, is efficacious and operates via caveolin-1-mediated endocytosis.

Cui, Tiantian; Corrales-Guerrero, Sergio; Castro-Aceituno, Veronica; Nair, Sindhu; Maneval, Daniel C; Monnig, Curtis; Kearney, Patrick; Ellis, Sam; Raheja, Nicholas; Raheja, Neil; Williams, Terence M

Cui, Tiantian; Corrales-Guerrero, Sergio; Castro-Aceituno, Veronica; Nair, Sindhu; Maneval, Daniel C; Monnig, Curtis; Kearney, Patrick; Ellis, Sam; Raheja, Nicholas; Raheja, Neil; Williams, Terence M.

Afiliación

Cui T; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USA.
Corrales-Guerrero S; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH 43210, USA.
Castro-Aceituno V; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USA.
Nair S; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USA.
Maneval DC; January Therapeutics, San Diego, CA 92121, USA.
Monnig C; January Therapeutics, San Diego, CA 92121, USA.
Kearney P; January Therapeutics, San Diego, CA 92121, USA.
Ellis S; January Therapeutics, San Diego, CA 92121, USA.
Raheja N; January Therapeutics, San Diego, CA 92121, USA.
Raheja N; January Therapeutics, San Diego, CA 92121, USA.
Williams TM; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USA.

Mol Ther Oncolytics ; 30: 181-192, 2023 Sep 21.

Article en En | MEDLINE | ID: mdl-37674628

Palabras clave

Cav-1; JNTX-101; albumin; caveolin-1; gemcitabine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Mol Ther Oncolytics Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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