Your browser doesn't support javascript.
loading
Prognostic value of illness perception on changes in knee pain among elderly individuals: Two-year results from the Frederiksberg Cohort study.
Ginnerup-Nielsen, Elisabeth; Christensen, Robin; Heitmann, Berit L; Altman, Roy D; March, Lyn; Woolf, Anthony; Bliddal, Henning; Henriksen, Marius.
Afiliación
  • Ginnerup-Nielsen E; The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
  • Christensen R; The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
  • Heitmann BL; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Denmark.
  • Altman RD; The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
  • March L; Section for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
  • Woolf A; Division of Rheumatology and Immunology, University of California, Los Angeles, CA 90095, USA.
  • Bliddal H; Florance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital, and Kolling Institute; and Sydney Muskuloskeletal Health, University of Sydney, NSW Australia.
  • Henriksen M; Bone and Joint Research Group, Royal Cornwall Hospital, Truro TR1 3HD, UK.
Osteoarthr Cartil Open ; 5(4): 100403, 2023 Dec.
Article en En | MEDLINE | ID: mdl-37671176
Objective: To investigate the prognostic value of illness perception (IP) on knee pain, quality of life (QoL) and functional level in elderly individuals reporting knee pain. Design: A prospective cohort study of 1552 elderly with knee pain comparing two previously established clusters based on the Brief Illness Perception questionnaire. Cluster 1 ("Concerned optimists" [hypothesized unfavorable profile]; n â€‹= â€‹642) perceived their knee pain as a greater threat to them than Cluster 2 ("Unconcerned confident" [hypothesized favorable profile]; n â€‹= â€‹910). Primary outcome was the change from baseline to year 2 in the KOOS Pain subscale. Secondary outcomes were changes from baseline in quality of life (EuroQol-5 Domain and EQ VAS) and in the KOOS subscales Symptom, Activities of Daily Living, Knee-related QoL and Sports and recreation. Analyses were done on the original Intention-To-Survey (ITS) population, using repeated measures mixed linear models. Results: Among the ITS population, 841 (54%) responded to the 2-year survey. There was a statistically significant but clinically irrelevant cluster difference in the 2-year change from baseline in KOOS pain (mean difference: 6.0 KOOS points [95% CI: 7.3 to -4.7]) explained by a minor improvement in Cluster 1: (6.2 points) and no changes in Cluster 2: (0.2 points). Comparable results were found across the secondary outcomes. Clinically irrelevant cluster changes in IP were seen. Conclusion: In a cohort of people with knee pain, IP phenotype (i.e., Clusters) were of no prognostic value for the 2-year changes in pain, function, and QoL. Targeting IP may not be relevant in this patient population. Trial registration number and date of registration: The Frederiksberg Cohort study was pre-registered at clinicaltrials.gov (NCT03472300) on March 21, 2018.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Aspecto: Patient_preference Idioma: En Revista: Osteoarthr Cartil Open Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Aspecto: Patient_preference Idioma: En Revista: Osteoarthr Cartil Open Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido