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Resolution of blood eosinophilia and limited mouth opening after short-term follow-up in a pediatric Langerhans cell histiocytosis case.
Reyes, Magdalena Raquel Torres; Javaroni, Julia Biliato; Nogueira, Gustavo Milhomens; Zelaya, Florence Juana Maria Cuadra; de León, Anyeli Soraya Alas; Silveira, Heitor Albergoni; León, Jorge Esquiche.
Afiliación
  • Reyes MRT; Department of Pediatric Dentistry - Riberão Preto Dental School (FORP/USP), University of São Paulo, Ribeirão Preto, São Paulo Brazil.
  • Javaroni JB; Department of Pediatric Dentistry - Riberão Preto Dental School (FORP/USP), University of São Paulo, Ribeirão Preto, São Paulo Brazil.
  • Nogueira GM; Department of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, São Paulo Brazil.
  • Zelaya FJMC; Department of Pathology and Diagnosis, School of Dentistry, University of El Salvador, San Salvador, El Salvador.
  • de León ASA; Dental Surgeon and Specialist in Oral and Maxillofacial Surgery, University of El Salvador, San Salvador, El Salvador.
  • Silveira HA; Oral Pathology, Department of Stomatology, Public Oral Health and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo , 14040-904 Ribeirão Preto, São Paulo Brazil.
  • León JE; Department of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, São Paulo Brazil.
Indian J Otolaryngol Head Neck Surg ; 75(3): 2568-2571, 2023 Sep.
Article en En | MEDLINE | ID: mdl-37636671
Introduction: Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia that often affects children, presenting a broad clinical spectrum. Methods: Here, we report a 13-year-old male Salvadorian patient who was referred presenting a nodular swelling at the mandibular angle region, mildly symptomatic, few weeks ago, which relevantly was associated with limited mouth opening. Intraoral examination was unremarkable. Imaginological exams revealed an osteolytic lesion affecting the vestibular cortex at the right mandibular angle. The blood test results were normal, except for eosinophilia (21%; absolute eosinophil count 4 × 109/L). After an incisional biopsy, microscopical and immunohistochemical analyses were consistent with LCH diagnosis, which corresponded to a single system-single site category. After a few weeks, the mandibular movements were re-established, and complete resolution of blood eosinophilia was observed. Conclusion: LCH with blood eosinophilia is rarely reported. To our knowledge, 3 cases have been previously published.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Otolaryngol Head Neck Surg Año: 2023 Tipo del documento: Article Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Otolaryngol Head Neck Surg Año: 2023 Tipo del documento: Article Pais de publicación: India