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Increased dental comorbidities in patients with psoriasis: a nationwide population-based cohort study in Korea.
Kwak, Eun-Jung; Choi, Yun Jin; Kim, Han-Na; Kim, Ko Eun; Jeon, Jiehyun; Baek, Yoo Sang.
Afiliación
  • Kwak EJ; National Dental Care Center for People with Special Needs, Seoul National University Dental Hospital, Seoul, Republic of Korea.
  • Choi YJ; Biomedical Research Institute, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Kim HN; Department of Dermatology, Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
  • Kim KE; Department of Dermatology, Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
  • Jeon J; Department of Dermatology, Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
  • Baek YS; Department of Dermatology, Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Clin Exp Dermatol ; 48(12): 1347-1353, 2023 Nov 16.
Article en En | MEDLINE | ID: mdl-37624999
BACKGROUND: Limited data are available regarding the association between psoriasis and common dental conditions. OBJECTIVES: To investigate the risk of potential dental comorbidities in patients with psoriasis. METHODS: We conducted a nationwide population-based cohort study to analyse the claims data of patients with psoriasis (n = 15 165) and age- and sex-matched controls (n = 75 825). The incidence risk of the following potential dental conditions was analysed: dental caries, pulp and periapical disease, periodontal disease, gingival changes and tooth loss. RESULTS: After adjusting for potential cofactors, the adjusted hazard ratios (aHRs) of dental caries [1.105; 95% confidence interval (CI) 1.078-1.132], pulp and periapical disease (1.07; 95% CI 1.044-1.096) and periodontal disease (1.108; 95% CI 1.088-1.129) were significantly higher than those in the control cohort (P < 0.001). However, among the subset of patients with psoriasis who received systemic antipsoriatic treatment (n = 4275), the aHR risk of all potential dental comorbidities was not significantly higher from that of the control cohort. CONCLUSIONS: Patients with psoriasis have an increased risk of dental comorbidities, and systemic antipsoriatic treatment may help mitigate this increased risk.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis / Caries Dental Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Clin Exp Dermatol Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis / Caries Dental Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Clin Exp Dermatol Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido