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Surf Redfish-Based ZnO-NPs and Their Biological Activity with Reference to Their Non-Target Toxicity.
Hasaballah, Ahmed I; El-Naggar, Hussein A; Abd-El Rahman, Ibrahim E; Al-Otibi, Fatimah; Alahmadi, Reham M; Abdelzaher, Othman F; Kalaba, Mohamed H; Amin, Basma H; Mabrouk, Mohamed M; Gewida, Ahmed G A; Abd El-Kader, Marwa F; Elbahnasawy, Mostafa A.
Afiliación
  • Hasaballah AI; Zoology and Entomology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
  • El-Naggar HA; Zoology and Entomology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
  • Abd-El Rahman IE; Department of Plant Protection, Faculty of Agriculture, Al-Azhar University, Cairo 32897, Egypt.
  • Al-Otibi F; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
  • Alahmadi RM; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
  • Abdelzaher OF; Zoology and Entomology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
  • Kalaba MH; Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
  • Amin BH; Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo 11884, Egypt.
  • Mabrouk MM; Fish Production Department, Faculty of Agriculture, Al-Azhar University, Cairo 32897, Egypt.
  • Gewida AGA; Fish Production Department, Faculty of Agriculture, Al-Azhar University, Cairo 32897, Egypt.
  • Abd El-Kader MF; Central Laboratory for Aquaculture Research, Sakha Aquaculture Research Unit, Department of Fish Diseases and Management, A.R.C., Kafrelsheikh 33516, Egypt.
  • Elbahnasawy MA; Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
Mar Drugs ; 21(8)2023 Aug 02.
Article en En | MEDLINE | ID: mdl-37623718
The marine environment is a rich source of bioactive compounds. Therefore, the sea cucumber was isolated from the Red Sea at the Al-Ain Al-Sokhna coast and it was identified as surf redfish (Actinopyga mauritiana). The aqueous extract of the surf redfish was utilized as an ecofriendly, novel and sustainable approach to fabricate zinc oxide nanoparticles (ZnO-NPs). The biosynthesized ZnO-NPs were physico-chemically characterized and evaluated for their possible antibacterial and insecticidal activities. Additionally, their safety in the non-target organism model (Nile tilapia fish) was also investigated. ZnO-NPs were spherical with an average size of 24.69 ± 11.61 nm and had a peak at 350 nm as shown by TEM and UV-Vis, respectively. XRD analysis indicated a crystalline phase of ZnO-NPs with an average size of 21.7 nm. The FTIR pattern showed biological residues from the surf redfish extract, highlighting their potential role in the biosynthesis process. DLS indicated a negative zeta potential (-19.2 mV) of the ZnO-NPs which is a good preliminary indicator for their stability. ZnO-NPs showed larvicidal activity against mosquito Culex pipiens (LC50 = 15.412 ppm and LC90 = 52.745 ppm) and a potent adulticidal effect to the housefly Musca domestica (LD50 = 21.132 ppm and LD90 = 84.930 ppm). Tested concentrations of ZnO-NPs showed strong activity against the 3rd larval instar. Topical assays revealed dose-dependent adulticidal activity against M. domestica after 24 h of treatment with ZnO-NPs. ZnO-NPs presented a wide antibacterial activity against two fish-pathogen bacteria, Pseudomonas aeruginosa and Aeromonas hydrophila. Histopathological and hematological investigations of the non-target organism, Nile tilapia fish exposed to 75-600 ppm ZnO-NPs provide dose-dependent impacts. Overall, data highlighted the potential applications of surf redfish-mediated ZnO-NPs as an effective and safe way to control mosquitoes, houseflies and fish pathogenic bacteria.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pepinos de Mar / Óxido de Zinc / Cíclidos / Nanopartículas / Culicidae Límite: Animals Idioma: En Revista: Mar Drugs Asunto de la revista: BIOLOGIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pepinos de Mar / Óxido de Zinc / Cíclidos / Nanopartículas / Culicidae Límite: Animals Idioma: En Revista: Mar Drugs Asunto de la revista: BIOLOGIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Suiza