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Primary versus salvage intratympanic steroid treatment for idiopathic sudden sensorineural hearing loss.
Lan, Wei-Che; Lin, Chia-Der; Tsou, Yung-An; Shih, Liang-Chun; Aoh, Yu; Lu, Chien-Chi; Hsu, Hsiu-San; Lai, Chun-Yu; Wang, Ching-Yuan.
Afiliación
  • Lan WC; Department of Otolaryngology Head and Neck Surgery China Medical University Hospital Taichung Taiwan.
  • Lin CD; Department of Otolaryngology Head and Neck Surgery China Medical University Hospital Taichung Taiwan.
  • Tsou YA; School of Medicine China Medical University Taichung Taiwan.
  • Shih LC; Department of Otolaryngology Head and Neck Surgery China Medical University Hospital Taichung Taiwan.
  • Aoh Y; School of Medicine China Medical University Taichung Taiwan.
  • Lu CC; Department of Otolaryngology Head and Neck Surgery China Medical University Hospital Taichung Taiwan.
  • Hsu HS; School of Medicine China Medical University Taichung Taiwan.
  • Lai CY; Department of Neurology China Medical University Hospital Taichung Taiwan.
  • Wang CY; Department of Otolaryngology Head and Neck Surgery China Medical University Hospital Taichung Taiwan.
Laryngoscope Investig Otolaryngol ; 8(4): 1029-1035, 2023 Aug.
Article en En | MEDLINE | ID: mdl-37621287
Objective: The objective of this research is to compare primary and salvage intratympanic (IT) steroid treatments in terms of hearing outcomes in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Methods: The patients were randomized into two (primary and salvage) groups. Both groups received systemic steroid treatment for 2 weeks. The primary group also received IT dexamethasone injection three times during the treatment period, whereas the salvage group received IT dexamethasone injection only if no or slight recovery was noted at the 2-week follow-up. If needed, salvage steroid injection was administered three times during the following 2 weeks. Hearing recovery was analyzed according to the modified American Academy of Otolaryngology-Head and Neck Surgery criteria. Results: The degrees of hearing improvement at the 3-month follow-up were similar in the two groups. Compared with baseline, the pure-tone average values and speech discrimination scores improved by 38.45 ± 21.95 dB HL and 34.32% ± 30.55%, respectively, in the primary group and 36.80 ± 22.33 dB HL and 31.87% ± 27.88%, respectively, in the salvage group (p = .762 and .659, respectively). In addition, the complete or partial hearing recovery rates were also similar in the primary and salvage groups (67.7% vs. 73.3%, respectively; p = .780). In the salvage group, 18 patients required no IT steroid injection because they recovered after systemic steroid treatment. Conclusion: Primary and salvage IT steroid treatments for ISSNHL led to similar outcomes. In summary, salvage IT steroid injection is recommended for patients with ISSNHL patients to prevent unnecessary IT injection. Level of evidence: 2.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Laryngoscope Investig Otolaryngol Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Laryngoscope Investig Otolaryngol Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos