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3D Printing of Interpenetrating Network Flexible Hydrogels with Enhancement of Adhesiveness.
Zhang, Lei; Du, Huifeng; Sun, Xin; Cheng, Feng; Lee, Wenhan; Li, Jiahe; Dai, Guohao; Fang, Nicholas Xuanlai; Liu, Yongmin.
Afiliación
  • Zhang L; Department of Mechanical & Industrial Engineering, Northeastern University, Boston, Massachusetts 02115, United States.
  • Du H; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yun Nan 650000, China.
  • Sun X; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
  • Cheng F; Department of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.
  • Lee W; Department of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts 02115, United States.
  • Li J; Department of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.
  • Dai G; Department of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.
  • Fang NX; Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Liu Y; Department of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.
ACS Appl Mater Interfaces ; 15(35): 41892-41905, 2023 Sep 06.
Article en En | MEDLINE | ID: mdl-37615397
3D printing of hydrogels has been widely explored for the rapid fabrication of complex soft structures and devices. However, using 3D printing to customize hydrogels with both adequate adhesiveness and toughness remains a fundamental challenge. Here, we demonstrate mussel-inspired (polydopamine) PDA hydrogel through the incorporation of a classical double network (2-acrylamido-2-methylpropanesulfonic acid) PAMPS/(polyacrylamide) PAAm to achieve simultaneously tailored adhesiveness, toughness, and biocompatibility and validate the 3D printability of such a hydrogel into customized architectures. The strategy of combining PDA with PAMPS/PAAm hydrogels leads to favorable adhesion on either hydrophilic or hydrophobic surfaces. The hydrogel also shows excellent flexibility, which is attributed to the reversible cross-linking of PDA and PAMPS, together with the long-chain PAAm cross-linking network. Among them, the reversible cross-linking of PDA and PAMPS is capable of dissipating mechanical energy under deformation. Meanwhile, the long-chain PAAm network contributes to maintaining a high deformation capability. We establish a theoretical framework to quantify the contribution of the interpenetrating networks to the overall toughness of the hydrogel, which also provides guidance for the rational design of materials with the desired properties. Our work manifests a new paradigm of printing adhesive, tough, and biocompatible interpenetrating network hydrogels to meet the requirements of broad potential applications in biomedical engineering, soft robotics, and intelligent and superabsorbent devices.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Impresión Tridimensional / Moléculas de Patrón Molecular Asociado a Patógenos Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Impresión Tridimensional / Moléculas de Patrón Molecular Asociado a Patógenos Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos