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A Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study.
Keske, Murat; Canda, Abdullah Erdem; Karadag, Mert Ali; Çiftçi, Halil; Erturhan, Sakip; Kactan, Cagri; Soytas, Mustafa; Özkaya, Fatih; Ozbey, Isa; Ordek, Eser; Atmaca, Ali Fuat; Yildirim, Asif; Sahin, Selcuk; Colakoglu, Yunus; Boylu, Ugur; Erol, Bulent; Caskurlu, Turhan; Kiremit, Murat Can; Cakici, Ozer Ural; Sonmez, Gokhan; Kiliçarslan, Hakan; Akbulut, Ziya; Kaygisiz, Onur; Bedir, Selahattin; Vuruskan, Hakan; Bozkurt, Yunus Erol; Aydin, Hasan Riza; Oguz, Ural; Basok, Erem Kaan; Gumus, Bilal Habes; Tuncel, Altug; Aslan, Yilmaz; Hamidi, Nurullah; Müslümanoglu, Ahmet Yaser; Dinçer, Murat; Balbay, Derya; Albayrak, Selami; Laguna, Maria Pilar.
Afiliación
  • Keske M; University of Health Sciences Medical Faculty of Kayseri, Kayseri City Hospital, Kayseri, Turkey.
  • Canda AE; Department of Urology, School of Medicine, Koç University, Istanbul, Turkey.
  • Karadag MA; University of Health Sciences Medical Faculty of Kayseri, Kayseri City Hospital, Kayseri, Turkey.
  • Çiftçi H; Department of Urology, School of Medicine, Harran University, Sanliurfa, Turkey.
  • Erturhan S; Department of Urology, School of Medicine, Gaziantep University, Gaziantep, Turkey.
  • Kactan C; Department of Urology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
  • Soytas M; Department of Urology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
  • Özkaya F; Department of Urology, School of Medicine, Atatürk University, Erzurum, Turkey.
  • Ozbey I; Department of Urology, School of Medicine, Atatürk University, Erzurum, Turkey.
  • Ordek E; Department of Urology, School of Medicine, Harran University, Sanliurfa, Turkey.
  • Atmaca AF; Department of Urology, Memorial Ankara Hospital, Ankara, Turkey.
  • Yildirim A; Department of Urology, School of Medicine, Medeniyet University, Istanbul, Turkey.
  • Sahin S; Department of Urology, University of Health Sciences Affiliated with Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
  • Colakoglu Y; Department of Urology, University of Health Sciences Affiliated with Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
  • Boylu U; Department of Urology, Istinye University Faculty of Medicine, Istanbul, Turkey.
  • Erol B; Department of Urology, School of Medicine, Medeniyet University, Istanbul, Turkey.
  • Caskurlu T; Department of Urology, School of Medicine, Medeniyet University, Istanbul, Turkey.
  • Kiremit MC; Department of Urology, School of Medicine, Koç University, Istanbul, Turkey.
  • Cakici OU; Department of Urology, Medical Park Ankara Hospital, Ankara, Turkey.
  • Sonmez G; Department of Urology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
  • Kiliçarslan H; Department of Urology, Uludag University, School of Medicine, Bursa, Turkey.
  • Akbulut Z; Department of Urology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
  • Kaygisiz O; Department of Urology, Uludag University, School of Medicine, Bursa, Turkey.
  • Bedir S; Department of Urology, University of Health Sciences Affiliated with Gulhane Training and Research Hospital, Ankara, Turkey.
  • Vuruskan H; Department of Urology, Uludag University, School of Medicine, Bursa, Turkey.
  • Bozkurt YE; Department of Urology, Celal Bayar University, School of Medicine, Manisa, Turkey.
  • Aydin HR; Department of Urology, University of Health Sciences Affiliated with Kanuni Training and Research Hospital, Trabzon, Turkey.
  • Oguz U; Department of Urology, Giresun University, School of Medicine, Giresun, Turkey.
  • Basok EK; Department of Urology, Medical Park Izmir Hospital, Izmir, Turkey.
  • Gumus BH; Department of Urology, Celal Bayar University, School of Medicine, Manisa, Turkey.
  • Tuncel A; Department of Urology, Ankara City Hospital, Ankara, Turkey.
  • Aslan Y; Department of Urology, Ankara City Hospital, Ankara, Turkey.
  • Hamidi N; Department of Urology, Ankara Abdurrahman Yurtaslan Oncology Hospital, Ankara, Turkey.
  • Müslümanoglu AY; Department of Urology, Bagcilar Training and Research Hospital, Istanbul, Turkey.
  • Dinçer M; Department of Urology, Bagcilar Training and Research Hospital, Istanbul, Turkey.
  • Balbay D; Department of Urology, School of Medicine, Koç University, Istanbul, Turkey.
  • Albayrak S; Department of Urology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
  • Laguna MP; Department of Urology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Urol Int ; 107(9): 857-865, 2023.
Article en En | MEDLINE | ID: mdl-37591208
INTRODUCTION: Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. METHODS: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible with testicular dysgenesis syndrome. Histology was categorized per size and risk groups. RESULTS: TSS was performed in 83 patients (86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 masses were benign and TGCTs, respectively. No statistical differences were observed in mean age (30.9 ± 10.32 years), pathological tumor size (14.67 ± 6.7 mm) between risk groups or between benign and malignant tumors (p = 0.608). When categorized per risk groups, 22 (73.3%) and 4 (7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups, respectively. Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5 ± 22.7 months, no patient developed systemic disease. Local recurrence was detected in 5 patients and received radical orchiectomy. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No erectile dysfunction was reported in patients with benign lesions. CONCLUSION: TSS is a safe and feasible approach with adequate cancer control, and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Testiculares / Anomalías Urogenitales Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Urol Int Año: 2023 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Testiculares / Anomalías Urogenitales Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Urol Int Año: 2023 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Suiza