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Pulsed thulium:YAG laser-ready to dust all urinary stone composition types? Results from a PEARLS analysis.
Kwok, Jia-Lun; Ventimiglia, Eugenio; De Coninck, Vincent; Corrales, Mariela; Sierra, Alba; Panthier, Frédéric; Pauchard, Felipe; Schmid, Florian; Hunziker, Manuela; Poyet, Cédric; Daudon, Michel; Traxer, Olivier; Eberli, Daniel; Keller, Etienne Xavier.
Afiliación
  • Kwok JL; Department of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
  • Ventimiglia E; Department of Urology, Tan Tock Seng Hospital, Singapore, Singapore.
  • De Coninck V; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.
  • Corrales M; Young Academic Urologists (YAU), Endourology and Urolithiasis Working Group, Arnhem, The Netherlands.
  • Sierra A; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
  • Panthier F; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.
  • Pauchard F; Young Academic Urologists (YAU), Endourology and Urolithiasis Working Group, Arnhem, The Netherlands.
  • Schmid F; Department of Urology, AZ Klina, Brasschaat, Belgium.
  • Hunziker M; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.
  • Poyet C; GRC n°20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
  • Daudon M; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.
  • Traxer O; Young Academic Urologists (YAU), Endourology and Urolithiasis Working Group, Arnhem, The Netherlands.
  • Eberli D; Urology Department, Hospital Clinic de Barcelona, Villarroel 170, 08036, Barcelona, Spain.
  • Keller EX; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.
World J Urol ; 41(10): 2823-2831, 2023 Oct.
Article en En | MEDLINE | ID: mdl-37587366
PURPOSE: To evaluate whether stone dust can be obtained from all prevailing stone composition types using the novel pulsed thulium:YAG (p-Tm:YAG), including analysis of stone particle size after lithotripsy. METHODS: Human urinary stones of 7 different compositions were subjected to in vitro lithotripsy using a p-Tm:YAG laser with 270 µm silica core fibers (Thulio®, Dornier MedTech GmbH®, Wessling, Germany). A cumulative energy of 1000 J was applied to each stone using one of three laser settings: 0.1 J × 100 Hz, 0.4 J × 25 Hz and 2.0 J × 5 Hz (average power 10 W). After lithotripsy, larger remnant fragments were separated from stone dust using a previously described method depending on the floating ability of dust particles. Fragments and dust samples were then passed through laboratory sieves to evaluate stone particle count according to a semiquantitative analysis relying on a previous definition of stone dust (i.e., stone particles ≤ 250 µm). RESULTS: The p-Tm:YAG laser was able to produce stone dust from lithotripsy up to measured smallest mesh size of 63 µm in all seven stone composition types. Notably, all dust samples from all seven stone types and with all three laser settings had high counts of particles in the size range agreeing with the definition stone dust, i.e., ≤ 250 µm. CONCLUSION: This is the first study in the literature proving the p-Tm:YAG laser capable of dusting all prevailing human urinary stone compositions, with production of dust particles ≤ 250 µm. These findings are pivotal for the broader future implementation of the p-Tm:YAG in clinical routine.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cálculos Urinarios / Litotripsia por Láser / Láseres de Estado Sólido Límite: Humans Idioma: En Revista: World J Urol Año: 2023 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cálculos Urinarios / Litotripsia por Láser / Láseres de Estado Sólido Límite: Humans Idioma: En Revista: World J Urol Año: 2023 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Alemania