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Distorted thoughts as a mediator of depressive symptoms in patients with major depressive disorder: a longitudinal study.
Carneiro, Adriana Munhoz; Pereira, Danilo Assis; Fernandes, Fernando; Baptista, Makilim Nunes; Brunoni, André Russowsky; Moreno, Ricardo Alberto.
Afiliación
  • Carneiro AM; Mood Disorders Unit, Faculty of Medicine FMUSP, University of Sao Paulo, BR Ovideo Pires de Campos St., São Paulo, SP, 785 05403-010, Brazil. adrianacarneiro01@gmail.com.
  • Pereira DA; Independent Consultant, Brasilia, Brazil.
  • Fernandes F; Mood Disorders Unit, Faculty of Medicine FMUSP, University of Sao Paulo, BR Ovideo Pires de Campos St., São Paulo, SP, 785 05403-010, Brazil.
  • Baptista MN; Laboratory of Psychometric Evaluation in Mental Health -LAPSAM III - São Francisco University, Campinas, Brazil.
  • Brunoni AR; Department of Internal Medicine, Faculty of Medicine FMUSP, University of Sao Paulo, São Paulo, SP, Brazil.
  • Moreno RA; Mood Disorders Unit, Faculty of Medicine FMUSP, University of Sao Paulo, BR Ovideo Pires de Campos St., São Paulo, SP, 785 05403-010, Brazil.
Health Qual Life Outcomes ; 21(1): 88, 2023 Aug 14.
Article en En | MEDLINE | ID: mdl-37580739
BACKGROUND: Distorted thoughts are common in Major Depressive Disorder (MDD), and can impact patients' perceptions of depression severity, and predict chronicity and treatment response. This study aimed to investigate whether distorted thoughts mediate depressive symptoms in MDD over a 6-month period. METHOD: These are secondary results from a study that followed 119 patients diagnosed with moderate to severe MDD for 6 months. Diagnoses were confirmed by the Structured Interview for DSM-IV (SCID-CV). The analysis was composed of results from the Hamilton Depression Rating Scale (HAMD-17), the Montgomery-Asberg Depression Rating Scale (MADRS), the second edition of the Beck Depression Inventory (BDI-II), and the Depression Thoughts Scale (DTS) collected at weeks 1, 8, 12 and 24. RESULTS: Results showed that the DTS mediated the relationship between depressive symptoms experienced approximately 3 months after starting antidepressant treatment. CONCLUSION: Cognitive distortions were linked as a mediator to depressive symptoms, highlighting the importance of early psychological interventions in patients with MDD who exhibit these distortions. TRIAL REGISTRATION: NCT02268487.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Depresivo Mayor Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Health Qual Life Outcomes Asunto de la revista: SAUDE PUBLICA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Depresivo Mayor Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Health Qual Life Outcomes Asunto de la revista: SAUDE PUBLICA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido