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Medical versus neurosurgical treatment in ICH patients: a single center experience.
Pierini, P; Novelli, Agnese; Bossi, F; Corinaldesi, R; Paciaroni, M; Mosconi, M G; Alberti, A; Venti, M; de Magistris, I Leone; Caso, V.
Afiliación
  • Pierini P; Department of Emergency Medicine, Città Di Castello Hospital, Città Di Castello, Italy.
  • Novelli A; Internal, Vascular and Emergency Medicine-Stroke Unit, Santa Maria della Misericordia University of Perugia, 06139, Perugia, Italy. agnese.novelli92@gmail.com.
  • Bossi F; Internal, Vascular and Emergency Medicine-Stroke Unit, Santa Maria della Misericordia University of Perugia, 06139, Perugia, Italy.
  • Corinaldesi R; Neurosurgery Department, Santa Maria Della Misericordia Hospital, Perugia, Italy.
  • Paciaroni M; Stroke Unit, Santa Maria Della Misericordia, University of Perugia, Perugia, Italy.
  • Mosconi MG; Stroke Unit, Santa Maria Della Misericordia, University of Perugia, Perugia, Italy.
  • Alberti A; Stroke Unit, Santa Maria Della Misericordia, University of Perugia, Perugia, Italy.
  • Venti M; Stroke Unit, Santa Maria Della Misericordia, University of Perugia, Perugia, Italy.
  • de Magistris IL; Stroke Unit, Santa Maria Della Misericordia, University of Perugia, Perugia, Italy.
  • Caso V; Stroke Unit, Santa Maria Della Misericordia, University of Perugia, Perugia, Italy.
Neurol Sci ; 45(1): 223-229, 2024 Jan.
Article en En | MEDLINE | ID: mdl-37578629
BACKGROUND AND AIMS: The effect of surgical treatment for spontaneous intracerebral hemorrhage (ICH) remains uncertain. We conducted an observational retrospective cohort study on supra-centimeter spontaneous ICH treated with either neurosurgical or conservative management. The baseline demographics and risk factors were correlated with in-hospital mortality and 3 and 6-month survival rates stratified by management. METHODS: We included all patients with evidence of spontaneous ICH > 1 cm detected by CT and admitted between august 2020 and march 2021 to the "SMM" Hospital in Perugia. RESULTS: Onehundredandtwentytwo patients were included in the study, and 45% (n.55) were surgically treated. The mean age was 71.9 ± 15.3, and 61% (n.75) were males. Intra-hospital mortality ended up being 31% (n.38), 3 months-survival was 63% (n.77) and 6 months-survival was 60% (n.73). From the multivariate analysis of the surgical patients versus medical patient, we observed that the surgical patients were younger (67.5 ± 14.9 vs 75.5 ± 14.7 y; OR 0.87; Cl 95% 0.85-0.94; p 0.001), with greater ICH volume at the onset (61 ± 39.4 cc vs 51 ± 64 cc; OR 1.03; Cl 95% 1.005-1.07; p 0.05), more midline shift (7.61 ± 5.54 mm vs 4.09 ± 5.88 mm; OR 1.37; Cl 95% 1.045-1.79; p 0.023), and a higher ICH score (3 vs 2 mean ICH score; OR 21.12; Cl 95% 2.6-170.6; p 0.004). Intra-hospital mortality in the surgical group and in the conservative treatment group was respectively 33% vs 30%, 3 month-survival was 64% vs 63% and 6 month- survival were 60% in both groups. CONCLUSIONS: Our patient cohort shows no overall benefit from surgery over conservative treatment, but surgical patients were younger and had larger ICH volume.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Cerebral Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Neurol Sci Asunto de la revista: NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Cerebral Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Neurol Sci Asunto de la revista: NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia