Inter-species differences between humans and other mammals in the in vitro metabolism of carbofuran and the role of human CYP enzymes.

Abass, Khaled; Reponen, Petri; Anyanwu, Brilliance; Pelkonen, Olavi

Abass, Khaled; Reponen, Petri; Anyanwu, Brilliance; Pelkonen, Olavi.

Afiliación

Abass K; Department of Environmental Health Sciences, College of Health Sciences, University of Sharjah, the United Arab Emirates; Sharjah Institute for Medical Research (SIMR), University of Sharjah, the United Arab Emirates; Research Unit of Biomedicine and Internal Medicine, Faculty of Medicine, Universit
Reponen P; Research Unit of Biomedicine and Internal Medicine, Faculty of Medicine, University of Oulu, Finland.
Anyanwu B; Department of Environmental Health Sciences, College of Health Sciences, University of Sharjah, the United Arab Emirates.
Pelkonen O; Research Unit of Biomedicine and Internal Medicine, Faculty of Medicine, University of Oulu, Finland.

Environ Toxicol Pharmacol ; 102: 104243, 2023 Sep.

Article en En | MEDLINE | ID: mdl-37572996

Asunto(s)

Carbofurano; Animales; Humanos; Carbofurano/toxicidad; Carbofurano/metabolismo; Citocromo P-450 CYP3A/metabolismo; Cromatografía Liquida; Especificidad de la Especie; Espectrometría de Masas en Tándem; Sistema Enzimático del Citocromo P-450/metabolismo; Microsomas Hepáticos/metabolismo; Mamíferos

Palabras clave

CYP P450s; Interspecies differences; LC-MS; Pesticides; Risk assessment; in vitro screening

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carbofurano Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Environ Toxicol Pharmacol Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos

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