Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.

Schmeing, Stefan; Amrahova, Gulshan; Bigler, Katrin; Chang, Jen-Yao; Openy, Joseph; Pal, Sunit; Posada, Laura; Gasper, Raphael; 't Hart, Peter

Schmeing, Stefan; Amrahova, Gulshan; Bigler, Katrin; Chang, Jen-Yao; Openy, Joseph; Pal, Sunit; Posada, Laura; Gasper, Raphael; 't Hart, Peter.

Afiliación

Schmeing S; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Amrahova G; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Bigler K; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Chang JY; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Openy J; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Pal S; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Posada L; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.
Gasper R; Crystallography and Biophysics Unit, Max-Planck-Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany.
't Hart P; Chemical Genomics Centre of the Max Planck Society, Max Planck Institute of Molecular Physiology Otto-Hahn-Strasse 11 44227 Dortmund Germany peter.t-hart@mpi-dortmund.mpg.de.

Chem Sci ; 14(31): 8269-8278, 2023 Aug 09.

Article en En | MEDLINE | ID: mdl-37564416

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Sci Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido

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