Biogenesis of fibrils requires C-mannosylation of PMEL.

Kawahara, Ryota; Usami, Tomoko; Arakawa, Satoko; Kamo, Hiroki; Suzuki, Takehiro; Komatsu, Ryosuke; Hara, Hiroyuki; Niwa, Yuki; Shimizu, Erina; Dohmae, Naoshi; Shimizu, Shigeomi; Simizu, Siro

Kawahara, Ryota; Usami, Tomoko; Arakawa, Satoko; Kamo, Hiroki; Suzuki, Takehiro; Komatsu, Ryosuke; Hara, Hiroyuki; Niwa, Yuki; Shimizu, Erina; Dohmae, Naoshi; Shimizu, Shigeomi; Simizu, Siro.

Afiliación

Kawahara R; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Usami T; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Arakawa S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Kamo H; Research Core, Institute of Research, Tokyo Medical and Dental University, Japan.
Suzuki T; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Komatsu R; Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Wako, Japan.
Hara H; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Niwa Y; Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine, Tokyo, Japan.
Shimizu E; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Dohmae N; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Shimizu S; Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Wako, Japan.
Simizu S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.

FEBS J ; 290(22): 5373-5394, 2023 11.

Article en En | MEDLINE | ID: mdl-37552474

Asunto(s)

Amiloide; Triptófano; Humanos; Glicosilación; Triptófano/genética; Triptófano/metabolismo; Amiloide/química; Melanosomas/genética; Melanosomas/metabolismo; Glicoproteínas/genética; Glicoproteínas/metabolismo; Proteínas Amiloidogénicas/metabolismo; Antígeno gp100 del Melanoma/genética; Antígeno gp100 del Melanoma/química; Antígeno gp100 del Melanoma/metabolismo

Palabras clave

C-mannosylation; PMEL; amyloid fibril; mass spectrometry; melanosome development

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triptófano / Amiloide Límite: Humans Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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