Inhibition of MC38 colon cancer growth by multicomponent chemoimmunotherapy with anti-IL-10R antibodies, HES-MTX nanoconjugate, depends on application of IL-12, IL-15 or IL-18 secreting dendritic cell vaccines.

Wegierek-Ciura, Katarzyna; Mierzejewska, Jagoda; Szczygiel, Agnieszka; Rossowska, Joanna; Wróblewska, Anna; Switalska, Marta; Goszczynski, Tomasz M; Szermer-Olearnik, Bozena; Pajtasz-Piasecka, Elzbieta

Wegierek-Ciura, Katarzyna; Mierzejewska, Jagoda; Szczygiel, Agnieszka; Rossowska, Joanna; Wróblewska, Anna; Switalska, Marta; Goszczynski, Tomasz M; Szermer-Olearnik, Bozena; Pajtasz-Piasecka, Elzbieta.

Afiliación

Wegierek-Ciura K; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Mierzejewska J; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Szczygiel A; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Rossowska J; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Wróblewska A; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Switalska M; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Goszczynski TM; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Szermer-Olearnik B; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Pajtasz-Piasecka E; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.

Front Immunol ; 14: 1212606, 2023.

Article en En | MEDLINE | ID: mdl-37545526

Asunto(s)

Vacunas contra el Cáncer; Neoplasias del Colon; Citocinas; Animales; Ratones; Células Dendríticas; Inmunoterapia/métodos; Interleucina-10; Interleucina-12; Interleucina-15; Interleucina-18; Metotrexato/farmacología; Metotrexato/uso terapéutico; Nanoconjugados/uso terapéutico; Microambiente Tumoral

Palabras clave

anti-IL-10R antibodies; colon carcinoma; dendritic cells; interleukin 12; interleukin 15; interleukin 18; methotrexate; nanoconjugate

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citocinas / Neoplasias del Colon / Vacunas contra el Cáncer Tipo de estudio: Guideline / Prognostic_studies Límite: Animals Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Suiza

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