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Neurologic Manifestations of Coronavirus Disease 2019 in Children: An Iranian Hospital-Based Study.
Haji Esmaeil Memar, Elmira; Heidari, Morteza; Ghabeli, Homa; Pourbakhtyaran, Elham; Haghighi, Roya; Hosseiny, Seyyed Mohammad Mahdi; Mamishi, Setareh; Mahmoudi, Shima; Eshaghi, Hamid; Tavasoli, Ali Reza; Mohammadi, Mahmoud; Shervin Badv, Reza; Zamani, Gholamreza; Ghahvehchi Akbari, Masood; Yarali, Bahram; Shirzadi, Rohola; Mohammadpour, Masoud; Yaghmaei, Bahareh; Sharifzadeh Ekbatani, Meisam; Najafi, Zeynab; Ashrafi, Mahmoud Reza.
Afiliación
  • Haji Esmaeil Memar E; Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Heidari M; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Ghabeli H; Myelin Disorders Clinic, Pediatric Neurology Division, Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.
  • Pourbakhtyaran E; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Haghighi R; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Hosseiny SMM; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mamishi S; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mahmoudi S; Department of Infectious Diseases, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Eshaghi H; Pediatric Infectious Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Tavasoli AR; Pediatric Infectious Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mohammadi M; Department of Infectious Diseases, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Shervin Badv R; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Zamani G; Myelin Disorders Clinic, Pediatric Neurology Division, Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.
  • Ghahvehchi Akbari M; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Yarali B; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Shirzadi R; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mohammadpour M; Department of Physical Medicine and Rehabilitation, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Yaghmaei B; Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Sharifzadeh Ekbatani M; Pediatric Respiratory and Sleep Medicine Research Center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Najafi Z; Department of Pediatric Intensive Care, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Ashrafi MR; Department of Pediatric Intensive Care, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med ; 26(3): 166-171, 2023 03 01.
Article en En | MEDLINE | ID: mdl-37543939
BACKGROUND: COVID-19 infection and its neurological manifestations were seen in children although less common than adults. The aim of this study was to determine the frequency of different types of neurologic findings of hospitalized children with COVID-19. ]. METHODS: This retrospective study was performed on hospitalized pediatric patients aged≤18 years with confirmed SARS-CoV-2 at Children's Medical Center Hospital. Neurological manifestations were defined as the presence of any of the following symptoms: seizure, altered mental status, behavioral/personality change, ataxia, stroke, muscle weakness, smell and taste dysfunctions, and focal neurological disorders. RESULTS: Fifty-four children with COVID-19 were admitted and their mean age was 6.94±4.06 years. Thirty-four of them (63%) were male. The most frequent neurological manifestation was seizure (19 [45%]) followed by muscle weakness (11 [26%]), loss of consciousness (10 [23%]), and focal neurological disorders (10 [23%]). Other neurological manifestations consisted of headache (n=7), movement disorders (n=6), behavioral/personality change (n=5), ataxia (n=3), and stroke (n=3). Twenty-nine percent of our patients had leukocytosis. A neutrophil count above 70% was seen in 31% of participants. Among our patients, 81% had a positive reverse-transcription polymerase chain reaction (RT-PCR) test for SARS-CoV-2. CONCLUSION: During the current pandemic outbreak, hospitalized children with COVID-19 should be evaluated for neurological signs because it is common among them and should not be under-estimated.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Accidente Cerebrovascular / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Child / Child, preschool / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Arch Iran Med Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Irán

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Accidente Cerebrovascular / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Child / Child, preschool / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Arch Iran Med Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Irán