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Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction.
Shimizu, Kotaro; Kikuta, Junichi; Ohta, Yumi; Uchida, Yutaka; Miyamoto, Yu; Morimoto, Akito; Yari, Shinya; Sato, Takashi; Kamakura, Takefumi; Oshima, Kazuo; Imai, Ryusuke; Liu, Yu-Chen; Okuzaki, Daisuke; Hara, Tetsuya; Motooka, Daisuke; Emoto, Noriaki; Inohara, Hidenori; Ishii, Masaru.
Afiliación
  • Shimizu K; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Kikuta J; WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Ohta Y; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Uchida Y; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, 565-0871, Japan. jkikuta@icb.med.osaka-u.ac.jp.
  • Miyamoto Y; WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan. jkikuta@icb.med.osaka-u.ac.jp.
  • Morimoto A; Laboratory of Bioimaging and Drug Discovery, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka, 567-0085, Japan. jkikuta@icb.med.osaka-u.ac.jp.
  • Yari S; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Sato T; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Kamakura T; WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Oshima K; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Imai R; WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Liu YC; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Okuzaki D; WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Hara T; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Motooka D; WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Emoto N; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Inohara H; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Ishii M; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
Nat Commun ; 14(1): 4417, 2023 08 03.
Article en En | MEDLINE | ID: mdl-37537159
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteogénesis / Colesteatoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteogénesis / Colesteatoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido