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Regulation of intestinal micro ecology between raw and salt-processed Alpinia oxyphylla on renal injury rats.
An, Jia; Xiao-Qiang, Huang; Shun-He, Liu; Zhi-Guang, Chang; Dong-Lin, Wang; Yin-Feng, Tan; Yong-Hui, Li.
Afiliación
  • An J; Medical School, Huanghe Science & Technology College, Zhengzhou, PR China.
  • Xiao-Qiang H; Medical School, Huanghe Science & Technology College, Zhengzhou, PR China.
  • Shun-He L; Medical School, Huanghe Science & Technology College, Zhengzhou, PR China.
  • Zhi-Guang C; Medical School, Huanghe Science & Technology College, Zhengzhou, PR China.
  • Dong-Lin W; Medical School, Huanghe Science & Technology College, Zhengzhou, PR China.
  • Yin-Feng T; Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Provincial Key Lab of R&D on Tropic Herbs, School of Pharmacy, Hainan Medical University, Haikou, PR China.
  • Yong-Hui L; Medical School, Huanghe Science & Technology College, Zhengzhou, PR China / Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Provincial Key Lab of R&D on Tropic Herbs, School of Pharmacy, Hainan Medical University, Haikou, PR China.
Pak J Pharm Sci ; 36(2): 557-564, 2023 Mar.
Article en En | MEDLINE | ID: mdl-37530165
Alpinia oxyphylla Fructus is one of the traditional Chinese medicine plants in the treatment of kidney injury. In clinical practice, crude Alpinia oxyphylla Fructus (CAOF) and salt-processed Alpinia oxyphylla Fructus (SAOF) are the two commonly used drugs specificated in the prevention and treatment of diabetic nephropathy (DN). However, the intestinal micro ecology regulation between CAOF and SAOF on DN has not been reported. In this paper, intestinal micro ecology regulation activities between CAOF and SAOF in DN rats were compared and analyzed by short-chain fatty acids (SCFAs) and intestinal flora analysis. The results showed that both SAOF and CAOF can regulate the intestinal flora metabolite SCFAs level in DN rats, reduce blood glucose concentration and improve inflammatory reaction. The intestinal flora analysis showed SAOF and CAOF could increase the intestinal bacterial diversity. The treatment of renal injury may be related to their increased intestinal bacterial diversity.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alpinia Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Pak J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article Pais de publicación: Pakistán
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alpinia Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Pak J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article Pais de publicación: Pakistán