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Funding and financial sustainability of pharmacovigilance: suggested models for funding pharmacovigilance in resource-limited African countries.
Isah, Ambrose O; Opadeyi, Abimbola O; Tumwijukye, Henry; Cobelens, Frank; Smith, Diede; Ndomondo-Sigonda, Margareth; Harmark, Linda; Tanui, Paul; Tiemersma, Edine; Mmbaga, Blandina T; Mahlangu, Gugu; Ayinbuomwan, Stephen A; Soulaymani, Rachida; Pandit, Jayesh M.
Afiliación
  • Isah AO; Department of Clinical Pharmacology and Therapeutics, School of Medicine, College of Medical Sciences, University of Benin/University of Benin Teaching Hospital, Benin City, Edo State PMB 1154, Nigeria.
  • Opadeyi AO; Department of Clinical Pharmacology and Therapeutics, University of Benin/University of Benin Teaching Hospital, Benin City, Nigeria.
  • Tumwijukye H; Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
  • Cobelens F; Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
  • Smith D; Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
  • Ndomondo-Sigonda M; African Union Development Agency-New Partnership for Africa's Development (AUDA-NEPAD), Midrand, Johannesburg, South Africa.
  • Harmark L; Netherlands Pharmacovigilance Centre Lareb, Den Bosch, The Netherlands.
  • Tanui P; African Union Development Agency-New Partnership for Africa's Development (AUDA-NEPAD), Midrand, Johannesburg, South Africa.
  • Tiemersma E; KNCV Tuberculosis Foundation, The Hague, The Netherlands.
  • Mmbaga BT; KNCV of the Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
  • Mahlangu G; Medicines Control Authority of Zimbabwe, Harare, Zimbabwe.
  • Ayinbuomwan SA; Department of Clinical Pharmacology and Therapeutics, University of Benin/University of Benin Teaching Hospital, Benin City, Nigeria.
  • Soulaymani R; WHO Collaborating Centre for Strengthening Pharmacovigilance Practices, Centre.
  • Pandit JM; Anti Poison et de Pharmacovigilance du Maroc, Rabat, Morocco.
Ther Adv Drug Saf ; 14: 20420986231188836, 2023.
Article en En | MEDLINE | ID: mdl-37529763
Funding models for pharmacovigilance in resource-limited African countries An important factor hindering the growth of pharmacovigilance (PV) in resource-limited settings following their entry into the WHO Programme of International Drug Monitoring is the lack of adequate funds to establish a functional National Pharmacovigilance System. This article provides an overview of various potential sources of funds in these settings and how they can be harnessed to fund PV. We undertook a review of PV financing in developed settings and carried out a landscape study of funding of PV in some African countries, as well as having an in-depth understanding of the PV system and the organisational structure. The nexus between the regulatory agencies and National Pharmacovigilance Centre was noted. We took into account the sources of funds, revenue pool, the disbursement of funds, budgeting and expenditure profile and the legal framework for the different African countries. We also identified the prevalent and potential sources of funds for PV. Consultative meetings, webinars and interviews with experts in PV were carried out as well. We discovered that most of the PV facilities were mainly integrated into the regulatory agencies regarding operational and fiscal governance with few facilities being independent of the regulatory agencies. The main source of funding was from the government with significant donor funding which is ad hoc and non-sustainable. Several potential sources were identified but yet to be exploited. There were no legal provisions for PV financing. We have now proposed funding models that may lead to increased revenue for PV in these countries as well as suggesting that a legal framework be provided to guarantee sustainability and address the nexus between the regulatory agencies and the PV outfits to ensure an appropriate share of resources and blocking diversions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Health_economic_evaluation / Prognostic_studies / Qualitative_research Idioma: En Revista: Ther Adv Drug Saf Año: 2023 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Health_economic_evaluation / Prognostic_studies / Qualitative_research Idioma: En Revista: Ther Adv Drug Saf Año: 2023 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Reino Unido