Your browser doesn't support javascript.
loading
Disease characteristics, pathogenesis, and treatment controversies of axial psoriatic arthritis.
Yousif, Patrick; Nahra, Vicky; Khan, Muhammad A; Magrey, Marina.
Afiliación
  • Yousif P; Division of Rheumatology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, OH, United States.
  • Nahra V; Division of Rheumatology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, OH, United States.
  • Khan MA; Case Western Reserve University School of Medicine, Cleveland, OH, United States.
  • Magrey M; Division of Rheumatology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, OH, United States. Electronic address: marina.magrey@uhhospitals.org.
Joint Bone Spine ; 91(1): 105625, 2024 Jan.
Article en En | MEDLINE | ID: mdl-37495073
Axial psoriatic arthritis (axPsA) has considerable overlap with axial spondyloarthritis (axSpA) but has some unique features that sometimes preclude classification into axSpA. It has some clinical and radiographic differences compared to axSpA. Imaging typically shows asymmetric syndesmophytes, mainly in the cervical spine, with less frequent sacroiliitis. It more commonly presents later in life and is associated with less severe inflammatory back pain than axSpA. The interleukin (IL) IL-23/IL-17 axis is central to the pathogenesis of both diseases. However, the response to therapies targeting these cytokines has been different. IL-23 inhibitors are ineffective in axSpA but may be effective in psoriatic arthritis (PsA). Recent post hoc analyses of clinical trial data with IL-23 inhibitors in PsA have raised the possibility of their efficacy in axPsA and need evaluation in future clinical trials. Moreover, there is a need for classification criteria for axPsA and better tools to assess therapeutic response.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Artritis Psoriásica / Espondiloartritis / Sacroileítis Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Joint Bone Spine Asunto de la revista: REUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Francia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Artritis Psoriásica / Espondiloartritis / Sacroileítis Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Joint Bone Spine Asunto de la revista: REUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Francia