Your browser doesn't support javascript.
loading
In-depth metataxonomic investigation reveals low richness, high intervariability, and diverse phylotype candidates of archaea in the human urogenital tract.
Kim, Yeon Bee; Whon, Tae Woong; Kim, Joon Yong; Kim, Juseok; Kim, Yujin; Lee, Se Hee; Park, Seong-Eun; Kim, Eun-Ju; Son, Hong-Seok; Roh, Seong Woon.
Afiliación
  • Kim YB; Kimchi Functionality Research Group, World Institute of Kimchi, Gwangju, 61755, Republic of Korea.
  • Whon TW; Interdisciplinary Program in Agricultural Genomics, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
  • Kim JY; Kimchi Functionality Research Group, World Institute of Kimchi, Gwangju, 61755, Republic of Korea.
  • Kim J; Microbiome Research Team, LISCure Biosciences Inc, Gyeonggi-do, 13486, Republic of Korea.
  • Kim Y; Microbiome Research Team, LISCure Biosciences Inc, Gyeonggi-do, 13486, Republic of Korea.
  • Lee SH; Kimchi Functionality Research Group, World Institute of Kimchi, Gwangju, 61755, Republic of Korea.
  • Park SE; Kimchi Functionality Research Group, World Institute of Kimchi, Gwangju, 61755, Republic of Korea.
  • Kim EJ; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.
  • Son HS; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.
  • Roh SW; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea. sonhs@korea.ac.kr.
Sci Rep ; 13(1): 11746, 2023 07 20.
Article en En | MEDLINE | ID: mdl-37474649
The urogenital microbiota is the potential principal factor in the pathophysiology of urinary tract infection and the protection of urinary tract health. Little is known about the urogenital archaeome although several reports have indicated that the archaeomes of various regions of the human body are associated with health. Accordingly, we aimed to determine the presence and diversity of archaeomes in the human urogenital tract. To explore the urogenital archaeome, voided urine specimens from 373 asymptomatic Korean individuals were used. No difference was observed in body mass index, age, or gender, according to presence of archaea. Analysis of archaeal 16S rRNA gene amplicons of archaea positive samples consisted of simple community structures, including diverse archaea, such as the phyla Methanobacteriota, Thermoproteota, and Halobacteriota. Asymptomatic individuals showed high participant-dependent intervariability in their urogenital archaeomes. The mean relative archaeal abundance was estimated to be 0.89%, and fluorescence in situ hybridisation micrographs provided evidence of archaeal cells in the human urogenital tract. In addition, the urogenital archaeome shared partial taxonomic compositional characteristics with those of the other body sites. In this study, Methanobacteriota, Thermoproteota, and Halobacteriota were suggested as inhabitants of the human urogenital tract, and a distinct human urogenital archaeome was characterised. These findings expand our knowledge of archaea-host associations in the human urogenital tract and may lead to novel insights into the role of archaea in urinary tract health.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Crenarchaeota / Euryarchaeota / Microbiota Límite: Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Crenarchaeota / Euryarchaeota / Microbiota Límite: Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido